Results 51 to 60 of about 167,560 (261)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Improving Podcast Distribution on Gwanda using PrivHab: a Multiagent Secure Georouting Protocol.

open access: yesAdvances in Distributed Computing and Artificial Intelligence Journal, 2015
We present PrivHab, a multiagent secure georouting protocol that improves podcast distribution on Gwanda, Zimbabwe. PrivHab learns the whereabouts of the nodes of the network to select an itinerary for each agent carrying a piece of data.
Adrián SÁNCHEZ-CARMONA   +2 more
doaj   +1 more source

A mobile agent infrastructure for the mobility support [PDF]

open access: yesProceedings of the 2000 ACM symposium on Applied computing - Volume 2, 2000
The mobility of terminals and users is a crucial issue in the open global system represented by the Internet. Supporting terminal and user mobility requires a middleware infrastructure capable of efficiently answering the needs of scalable resource discovery, of security and interoperability, of Quality of Service (QoS) monitoring and adaptation.
Paolo Bellavista   +2 more
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Distributed and Collaborative Intelligent System for Medical Diagnosis

open access: yesAdvances in Distributed Computing and Artificial Intelligence Journal, 2013
In this paper, we present a distributed collaborative system assisting physicians in diagnosis when processing medical images. This is a Web-based solution since the different participants and resources are on various sites.
Naoufel KHAYATI, Wided LEJOUAD-CHAARI
doaj   +1 more source

Testing Mobile Agents [PDF]

open access: yes, 2002
For years to come, we can predict an important increase in the use of software systems using mobile code. Those systems give birth to new development problems compared to current distributed systems. In particular, testing for such systems must take into account the mobility of tested processes, which makes it difficult to maintain contact points ...
Mikael Marche   +2 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Novel mobile agent dynamic data integrity protection protocol

open access: yesTongxin xuebao, 2007
Integrity characteristics of dynamic data was redefined and classified by attacker capability,and then it was analyzed how to protect truncation attack with collusion.After that,a data protection protocol of free-roaming agent was presented.The protocol ...
LI Peng-fei1   +3 more
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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