Results 41 to 50 of about 1,570,465 (276)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The regulation of mobile health applications
BMC Medicine, 2012 In July 2011, the United States Food and Drug Administration issued draft guidance concerning the regulation of mobile medical applications (applications on a wireless device that are used as accessories to medical devices or to convert a mobile platform
Barton Amy J
doaj +1 more source
The implementation of persuasive technology principles in mobile application development: a qualitative study [PDF]
, 2017 Preceding studies of persuasive technology have mentioned several benefits on the implementation of persuasive design features of the Persuasive System Design (PSD) model such as creating users' engagement and acceptance and continuous usage.
Shafin, Noor Afifah
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Scope of Mobile Apps in Health Domain: Highlighting Applications Recommended by Known Organizations [PDF]
Taṣvīr-i salāmat, 2012 Background and objectives : With over one billion smartphones and 100 million tablets across the world, they can perform as a valuable tool in health care management and transform health care through using mobile applications.
Navideh Khodaei +2 more
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cogent Food & Agriculture, 2023 In Kenya, smartphones are readily available at lower cost than before, allowing farmers to access agricultural information through mobile applications. However, despite increased ownership of smartphones and the availability of mobile applications, the ...
Samuel P. Mutuma +3 more
doaj +1 more source
Impact factors for mobile internet applications in the agri-food sectors [PDF]
, 2006 Mobile communication and the mobile Internet can provide important opportunities, economic advantages for enterprises end organisations and support their more efficient operating as they can be used anytime and anywhere.
Herdon, Miklós, Szilágyi, Róbert
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source