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The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Factors Influencing the Quality of Mobile Applications [PDF]
Mobile applications are becoming increasingly used. Mobile devices are becoming indispensable for the user. In the material are claiming the sales of mobile devices internationally and the use of mobile applications compared to traditional internet use ...
Alin ZAMFIROIU
doaj +1 more source
Mobile Applications in X-KLAIM [PDF]
Networking has turned computers from isolated data processors into powerful communication and elaboration devices, called global computers; an illustrative example is the World–Wide Web.
Bettini, Lorenzo +3 more
core +1 more source
Using mobile RE tools to give end-users their own voice [PDF]
Researchers highlight end-user involvement in system design as an important concept for developing useful and usable solutions. However, end-user involvement in software engineering is still an open-ended topic.
Graf, F., Maiden, N., Seyff, N.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Adaptable Mobile Applications: Exploiting Logical Mobility in Mobile Computing [PDF]
An increasing number of applications is being written for mobile hosts, such as laptop computers, mobile phones, PDAs etc. These applications are usually monolithic, featuring very limited interoperability and context-awareness and are usually difficult to deploy and update.
Zachariadis, S, Mascolo, C, Emmerich, W
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
SOFTWARE APPLICATIONS FOR MOBILE AND MOBILE PROTECTION [PDF]
One of the most interesting hipothesys launched in the software industries reveals the following: software applications modify intentions, consumer behavior and all related to the motivation.
Ştefan IOVAN, Cristian IVĂNUŞ
doaj
Possibilities of using beacons in advertising
Beacon is a device, that broadcasts its identifier via Bluetooth Low Energy signal to nearby mobile devices, like smartphones or tablets. A special application installed on user’s device serves additional functionalities, that improves general user ...
Konrad Łyda, Marek Miłosz
doaj +1 more source
Mobile Internet Applications, Infrastructure and Services [PDF]
Mobile communication and the mobile Internet can provide important opportunities, economic advantages for enterprises end organisations and support their more efficient operating as they can be used anytime and anywhere.
Herdon, Miklós, Szilágyi, Róbert
core

