Results 61 to 70 of about 73,811 (267)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Cellular Operator Data Meets Counterfactual Machine Learning

IEEE Access
Unlicensed cellular networks and spectrum-sharing standards assist operators in meeting the ever-increasing demand for mobile data. However, several incumbents are already operational in these frequencies, rendering the wireless environment extremely ...
Srikant Manas Kala, Malvika Mishra, Vanlin Sathya, Tatsuya Amano, Monisha Ghosh, Teruo Higashino, Hirozumi Yamaguchi   +6 more
doaj   +1 more source

Service Management for IoT: Requirements, Taxonomy, Recent Advances and Open Research Challenges

IEEE Access, 2019
The exponential growth in the number of smart devices connected to the Internet of Things (IoT), and associated with various IoT-based smart applications and services, raises interoperability challenges which could affect the sustainability of IoT ...
Abdelmuttlib Ibrahim Abdalla Ahmed, Abdullah Gani, Siti Hafizah Ab Hamid, Abdelzahir Abdelmaboud, Hassan Jamil Syed, Riyaz Ahamed Ariyaluran Habeeb Mohamed, Ihsan Ali   +6 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Dynamic and efficient device collaborations in 5G‐advanced and 6G networks

IET Communications
Collaborative transmission, comprising multiple devices owned by a single user, is progressively evolving into an essential strategy to meet the stringent demands of burgeoning collaborative scenarios in 5G‐advanced and 6G networks.
Xianghui Han, Shuai Zhou, Shuaihua Kou, Jian Li, Ruiqi Liu, Shi Jin   +5 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Environmental-structure-perception-based adaptive pose fusion method for LiDAR-visual-inertial odometry

International Journal of Advanced Robotic Systems
Light Detection and Ranging (LiDAR)-visual-inertial odometry can provide accurate poses for the localization of unmanned vehicles working in unknown environments in the absence of Global Positioning System (GPS).
Zixu Zhao, Chang Liu, Wenyao Yu, Jinglin Shi, Dalin Zhang   +4 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source