Results 71 to 80 of about 67,167 (267)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Toward mobile learning deployment in higher education [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Mobile Learning (M-learning) refers to any kind of learning which takes place within and beyond the traditional learning environment via wireless mobile ...
Abu-Al-Aish, Ahmad
core  

Benign and malignant diagnosis of spinal tumors based on deep learning and weighted fusion framework on MRI

Insights into Imaging, 2022
Background The application of deep learning has allowed significant progress in medical imaging. However, few studies have focused on the diagnosis of benign and malignant spinal tumors using medical imaging and age information at the patient level. This
Hong Liu, Menglei Jiao, Yuan Yuan, Hanqiang Ouyang, Jianfang Liu, Yuan Li, Chunjie Wang, Ning Lang, Yueliang Qian, Liang Jiang, Huishu Yuan, Xiangdong Wang   +11 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Exploiting reflection in mobile computing middleware [PDF]

, 2002
The increasing popularity of portable devices and recent advances in wireless networking technologies facilitate the engineering of new classes of applications, which present challenging problems to designers.
Mascolo, C., Mascolo, C, Grace, P, Blair, GS, Grace, P., Capra, L, Blair, Gordon S., ,, Emmerich, W, Capra, L., Emmerich, W.   +10 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Dynamic and efficient device collaborations in 5G‐advanced and 6G networks

IET Communications
Collaborative transmission, comprising multiple devices owned by a single user, is progressively evolving into an essential strategy to meet the stringent demands of burgeoning collaborative scenarios in 5G‐advanced and 6G networks.
Xianghui Han, Shuai Zhou, Shuaihua Kou, Jian Li, Ruiqi Liu, Shi Jin   +5 more
doaj   +1 more source

Cellular Operator Data Meets Counterfactual Machine Learning

IEEE Access
Unlicensed cellular networks and spectrum-sharing standards assist operators in meeting the ever-increasing demand for mobile data. However, several incumbents are already operational in these frequencies, rendering the wireless environment extremely ...
Srikant Manas Kala, Malvika Mishra, Vanlin Sathya, Tatsuya Amano, Monisha Ghosh, Teruo Higashino, Hirozumi Yamaguchi   +6 more
doaj   +1 more source

Service Management for IoT: Requirements, Taxonomy, Recent Advances and Open Research Challenges

IEEE Access, 2019
The exponential growth in the number of smart devices connected to the Internet of Things (IoT), and associated with various IoT-based smart applications and services, raises interoperability challenges which could affect the sustainability of IoT ...
Abdelmuttlib Ibrahim Abdalla Ahmed, Abdullah Gani, Siti Hafizah Ab Hamid, Abdelzahir Abdelmaboud, Hassan Jamil Syed, Riyaz Ahamed Ariyaluran Habeeb Mohamed, Ihsan Ali   +6 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source