Results 51 to 60 of about 994,283 (339)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

IEEE Access Special Section Editorial: Mobile Edge Computing and Mobile Cloud Computing: Addressing Heterogeneity and Energy Issues of Compute and Network Resources

open access: yesIEEE Access, 2020
Mobile applications are advancing toward higher network and compute requirements, which are similar to the requirements of server applications. Users prefer to perform their tasks on the go from mobile devices instead of stationary desktop and server ...
Muhammad Khurram Khan   +6 more
doaj   +1 more source

Optimal Pricing-Based Edge Computing Resource Management in Mobile Blockchain

open access: yes, 2017
As the core issue of blockchain, the mining requires solving a proof-of-work puzzle, which is resource expensive to implement in mobile devices due to high computing power needed.
Feng, Shaohan   +4 more
core   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Optimizing strategy of computing off loading energy consumption based on Lagrangian method

open access: yesDianxin kexue, 2018
With the development of mobile network technology and the popularization and application of intelligent terminals,mobile edge computing has become an important application of cloud computing.Computing offloading strategy has become one of the key issues ...
Guangxue YUE   +5 more
doaj   +2 more sources

Edge computing based incentivizing mechanism for mobile blockchain in IOT [PDF]

open access: yesarXiv, 2020
Mining in the blockchain requires high computing power to solve the hash puzzle for example proof-of-work puzzle. It takes high cost to achieve the calculation of this problem in devices of IOT, especially the mobile devices of IOT. It consequently restricts the application of blockchain in mobile environment. However, edge computing can be utilized to
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

A Taxonomy for Management and Optimization of Multiple Resources in Edge Computing

open access: yes, 2018
Edge computing is promoted to meet increasing performance needs of data-driven services using computational and storage resources close to the end devices, at the edge of the current network.
Nadjm-Tehrani, Simin, Toczé, Klervie
core   +1 more source

Mobile Edge Computing: A Survey on Architecture and Computation Offloading [PDF]

open access: yesIEEE Communications Surveys & Tutorials, 2017
28 pages, 21 figures, Accepted for publication in IEEE Communications Surveys and ...
Pavel Mach, Zdenek Becvar
openaire   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy