Results 61 to 70 of about 3,766,810 (246)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Joint Allocation of Computing and Wireless Resources to Autonomous Devices in Mobile Edge Computing

, 2018
We consider the interaction between mobile edge computing (MEC) resource management and wireless devicesthat offload computationally intensive tasks through shared wireless links to edge cloud servers, so as to minimize their completion times.
Josilo, Sladana, Dán, György, Josilo, Sladana,, Dán, György,, György Dán, Slađana Jošilo   +5 more
core   +1 more source

Resource allocation models in/for edge computing

, 2020
During last decades, cloud computing enabled centralization of computing, storage and network management through cloud data centres, cellular core networks and backbone IP networks. Unlimited computing resources and storage can be used to provide elastic
Taheri, Javid,, Khoshkholghi, Mohammad Ali,, Gokan Khan, Michel,, Sharma, Yogesh,   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

A micro-economic approach to conflict resolution in mobile computing [PDF]

, 2002
Mobile devices, such as mobile phones and personal digital assistants, have gained wide-spread popularity. These devices will increasingly be networked, thus enabling the construction of distributed mobile applications.
Licia Capra, Mascolo, C, Cecilia Mascolo, Capra, L, Wolfgang Emmerich, Emmerich, W   +5 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Dynamic Computation Offloading Based on Graph Partitioning in Mobile Edge Computing

IEEE Access, 2019
Mobile edge computing is a new cloud computing paradigm that utilizes small-sized edge clouds to provide real-time services to users. These mobile edge clouds (MECs) are located near users, thereby enabling users to seamlessly access applications that ...
Guangshun Li, Qingyan Lin, Junhua Wu, Ying Zhang, Jiahe Yan   +4 more
doaj   +1 more source