Results 71 to 80 of about 459,637 (360)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Cloud/fog computing resource management and pricing for blockchain networks

open access: yes, 2018
The mining process in blockchain requires solving a proof-of-work puzzle, which is resource expensive to implement in mobile devices due to the high computing power and energy needed.
Feng, Shaohan   +5 more
core   +1 more source

Computation Rate Maximization for Wireless Powered Mobile-Edge Computing With Binary Computation Offloading [PDF]

open access: yesIEEE Transactions on Wireless Communications, 2017
Finite battery lifetime and low computing capability of size-constrained wireless devices (WDs) have been longstanding performance limitations of many low-power wireless networks, e.g., wireless sensor networks and Internet of Things.
Suzhi Bi, Y. Zhang
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Performance Evaluation of Integrated Multi-Access Edge Computing and Fiber-Wireless Access Networks

open access: yesIEEE Access, 2018
With the widespread use of smart mobile devices, the exponential growth of mobile Internet traffic and newly emerging services, such as Internet of Things, virtual reality/augmented reality, and serious games, the network performance requirements for ...
Jing Liu   +4 more
doaj   +1 more source

Cross-Server Computation Offloading for Multi-Task Mobile Edge Computing

open access: yesInformation, 2020
As an emerging network architecture and technology, mobile edge computing (MEC) can alleviate the tension between the computation-intensive applications and the resource-constrained mobile devices.
Yongpeng Shi, Yujie Xia, Ya Gao
doaj   +1 more source

Optimal Pricing-Based Edge Computing Resource Management in Mobile Blockchain

open access: yes, 2017
As the core issue of blockchain, the mining requires solving a proof-of-work puzzle, which is resource expensive to implement in mobile devices due to high computing power needed.
Feng, Shaohan   +4 more
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Artificial Intelligence-Empowered Edge of Vehicles: Architecture, Enabling Technologies, and Applications

open access: yesIEEE Access, 2020
With the proliferation of mobile devices and a wealth of rich application services, the Internet of vehicles (IoV) has struggled to handle computationally intensive and delay-sensitive computing tasks.
Hongjing Ji, Osama Alfarraj, Amr Tolba
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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