Results 11 to 20 of about 853 (166)

Genomic Island-Encoded Diguanylate Cyclase from Vibrio alginolyticus Regulates Biofilm Formation and Motility in Pseudoalteromonas

Microorganisms, 2023
Many bacteria use the second messenger c-di-GMP to regulate exopolysaccharide production, biofilm formation, motility, virulence, and other phenotypes.
Tongxuan Cai, Huan Tang, Xiaofei Du, Weiquan Wang, Kaihao Tang, Xiaoxue Wang, Dong Liu, Pengxia Wang   +7 more
doaj   +1 more source

Importance of mobile genetic element immunity in numerically abundant Trichodesmium clades

ISME Communications, 2023
The colony-forming cyanobacteria Trichodesmium spp. are considered one of the most important nitrogen-fixing genera in the warm, low nutrient ocean. Despite this central biogeochemical role, many questions about their evolution, physiology, and trophic ...
Eric A. Webb, Noelle A. Held, Yiming Zhao, Elaina D. Graham, Asa E. Conover, Jake Semones, Michael D. Lee, Yuanyuan Feng, Fei-xue Fu, Mak A. Saito, David A. Hutchins   +10 more
doaj   +1 more source

Identifying insertion mutations by whole-genome sequencing

BioTechniques, 2011
Insertion mutagenesis via mobile genetic element is a common technique for the analysis of gene function in model organisms. Next-generation sequencing offers an attractive approach for localizing the site of insertion, but alignment-based mapping of ...
Harold E. Smith
doaj   +1 more source

A Mobile Element in mutS Drives Hypermutation in a Marine Vibrio

mBio, 2017
Bacteria face a trade-off between genetic fidelity, which reduces deleterious mistakes in the genome, and genetic innovation, which allows organisms to adapt. Evidence suggests that many bacteria balance this trade-off by modulating their mutation rates,
Nathaniel D. Chu, Sean A. Clarke, Sonia Timberlake, Martin F. Polz, Alan D. Grossman, Eric J. Alm   +5 more
doaj   +1 more source

A comprehensive map of mobile element insertion polymorphisms in humans. [PDF]

PLoS Genetics, 2011
As a consequence of the accumulation of insertion events over evolutionary time, mobile elements now comprise nearly half of the human genome. The Alu, L1, and SVA mobile element families are still duplicating, generating variation between individual ...
Chip Stewart, Deniz Kural, Michael P Strömberg, Jerilyn A Walker, Miriam K Konkel, Adrian M Stütz, Alexander E Urban, Fabian Grubert, Hugo Y K Lam, Wan-Ping Lee, Michele Busby, Amit R Indap, Erik Garrison, Chad Huff, Jinchuan Xing, Michael P Snyder, Lynn B Jorde, Mark A Batzer, Jan O Korbel, Gabor T Marth, 1000 Genomes Project   +20 more
doaj   +1 more source

WHOLE GENOME SEQUENCING REVEALS DIVERSE MODES OF CARBAPENEMASE GENE DISSEMINATION IN INDIAN KLEBSIELLA PNEUMONIAE CLINICAL ISOLATES

International Journal of Infectious Diseases, 2023
Intro: Mobile genetic elements and plasmids harboring multiple drug resistance genes are a significant concern in Klebsiella pneumoniae causing nosocomial infections.
V. Shamanna, A. Underwood, S. Argimón, A. Prasanna, G. Nagaraj, V. Govindan, D. Aanensen, K.L. Ravikumar   +7 more
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A Novel aadA Aminoglycoside Resistance Gene in Bovine and Porcine Pathogens

mSphere, 2018
A novel variant of the AAD(3″) class of aminoglycoside-modifying enzymes was discovered in fatal bovine respiratory disease-associated pathogens Pasteurella multocida and Histophilus somni.
Andrew Cameron, Cassidy L. Klima, Reuben Ha, Robert J. Gruninger, Rahat Zaheer, Tim A. McAllister   +5 more
doaj   +1 more source

Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element

Mobile DNA, 2020
Background Mobile genetic elements are found in genomes throughout the microbial world, mediating genome plasticity and important prokaryotic phenotypes.
Birgit Henrich, Stephanie Hammerlage, Sebastian Scharf, Diana Haberhausen, Ursula Fürnkranz, Karl Köhrer, Lena Peitzmann, Pier Luigi Fiori, Joachim Spergser, Klaus Pfeffer, Alexander T. Dilthey   +10 more
doaj   +1 more source

Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. [PDF]

PLoS Pathogens, 2009
Bacterial virulence and antibiotic resistance have a significant influence on disease severity and treatment options during bacterial infections. Frequently, the underlying genetic determinants are encoded on mobile genetic elements (MGEs).
Shu Y Queck, Burhan A Khan, Rong Wang, Thanh-Huy L Bach, Dorothee Kretschmer, Liang Chen, Barry N Kreiswirth, Andreas Peschel, Frank R Deleo, Michael Otto   +9 more
doaj   +1 more source

Suspended Materials in River Waters Differentially Enrich Class 1 Integron- and IncP-1 Plasmid-Carrying Bacteria in Sediments

Frontiers in Microbiology, 2018
Aquatic ecosystems are frequently considered as the final receiving environments of anthropogenic pollutants such as pharmaceutical residues or antibiotic resistant bacteria, and as a consequence tend to form reservoirs of antibiotic resistance genes ...
Magali De la Cruz Barrón, Christophe Merlin, Hélène Guilloteau, Emmanuelle Montargès-Pelletier, Emmanuelle Montargès-Pelletier, Xavier Bellanger   +5 more
doaj   +1 more source