Identifying Structural Variation in Haploid Microbial Genomes from Short-Read Resequencing Data Using Breseq [PDF]
Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes.
Barrick, Jeffrey E. +8 more
core +1 more source
Gene transfer in the GI tract and oral cavity [PDF]
Gene transfer is important in spreading antibiotic resistance and other traits such as virulence factors. In this review the molecular mechanisms of gene transfer are outlined and the biological consequences of bacterial gene transfer in the GI tract and
Mullany, P
core +1 more source
Mobile Genetic Elementsevolves [PDF]
Dear Reader: It is with great pleasure that we can report that MGE now begins its fourth volume. In its first three years MGE has continued to attract high quality research articles, reviews and a lively selection of commentaries which cut across all domains of life.
Adam P, Roberts +2 more
openaire +2 more sources
Shuffling of mobile genetic elements (MGEs) in successful healthcare-associated MRSA (HA-MRSA). [PDF]
Methicillin-resistant Staphylococcus aureus (MRSA) CC22 SCCmecIV is a successful hospital-associated (HA-) MRSA, widespread throughout the world, and now the dominant clone in UK hospitals.
Budd, EL +3 more
core +1 more source
Integrated mobile genetic elements in Thaumarchaeota [PDF]
Summary To explore the diversity of mobile genetic elements (MGE) associated with archaea of the phylum Thaumarchaeota, we exploited the property of most MGE to integrate into the genomes of their hosts. Integrated MGE (iMGE) were identified in 20 thaumarchaeal genomes amounting to 2 Mbp of mobile thaumarchaeal ...
Krupovic, M +6 more
openaire +2 more sources
Identification of mobile genetic elements with geNomad
Abstract Identifying and characterizing mobile genetic elements in sequencing data is essential for understanding their diversity, ecology, biotechnological applications and impact on public health. Here we introduce geNomad, a classification and annotation framework that combines information from gene content and
Antonio Pedro Camargo +8 more
openaire +5 more sources
Neutral genomic microevolution of a recently emerged pathogen, salmonella enterica serovar agona [PDF]
Salmonella enterica serovar Agona has caused multiple food-borne outbreaks of gastroenteritis since it was first isolated in 1952. We analyzed the genomes of 73 isolates from global sources, comparing five distinct outbreaks with sporadic infections as
Achtman, Mark +9 more
core +3 more sources
Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob +2 more
core +1 more source
Detection of VIM-1-producing Enterobacter cloacae and Salmonella enterica Serovars Infantis and Goldcoast at a breeding pig farm in Germany in 2017 and their molecular relationship to former VIM-1-producing S. Infantis Isolates in German livestock production [PDF]
In 2011, VIM-1-producing Salmonella enterica serovar Infantis and Escherichia coli were isolated for the first time in four German livestock farms. In 2015/2016, highly related isolates were identified in German pig production.
Borowiak, Maria +9 more
core +1 more source
Mobile genetic elements of Staphylococcus aureus [PDF]
Bacteria such as Staphylococcus aureus are successful as commensal organisms or pathogens in part because they adapt rapidly to selective pressures imparted by the human host. Mobile genetic elements (MGEs) play a central role in this adaptation process and are a means to transfer genetic information (DNA) among and within bacterial species ...
Malachowa, Natalia, DeLeo, Frank R.
openaire +2 more sources

