Results 221 to 230 of about 68,518 (254)
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Mutational Analysis of sRNA–mRNA Base Pairing by Electrophoretic Mobility Shift Assay
2018Small regulatory RNAs (sRNAs) in bacteria often act by base pairing to mRNAs. Direct interactions between an sRNA and its target mRNA can be investigated by electrophoretic mobility shift assay. In this assay, regions engaged in base pairing are analyzed by introducing mutations in one of the RNAs that prevent sRNA-mRNA complex formation, followed by ...
Lillebæk, Eva Maria Sternkopf +1 more
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Arabidopsis cyclophilins direct intracellular transport of mobile mRNA via organelle hitchhiking
Nature PlantsPlants convert external cues into mobile mRNAs to synchronize meristematic differentiation with environmental dynamics. These mRNAs are selectively transported to intercellular pores, plasmodesmata (PD), for cell-to-cell movement. However, how plants recognize and deliver mobile mRNAs to PD remains unknown.
Kai-Ren Luo +4 more
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Molecular Brain Research, 1994
Functional expression of opioid receptors was detected in the Xenopus oocyte translation system by a voltage-clamp recording. After injection of poly(A)+ RNA isolated from 3-week-old rat striatum or whole brain, the oocytes often demonstrated intracellular Ca(2+)-mediated oscillatory responsiveness to [D-Ala2, N-methyl-Phe4, Gly5-ol]enkephalin (DAMGO),
S, Kaneko +3 more
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Functional expression of opioid receptors was detected in the Xenopus oocyte translation system by a voltage-clamp recording. After injection of poly(A)+ RNA isolated from 3-week-old rat striatum or whole brain, the oocytes often demonstrated intracellular Ca(2+)-mediated oscillatory responsiveness to [D-Ala2, N-methyl-Phe4, Gly5-ol]enkephalin (DAMGO),
S, Kaneko +3 more
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Shock, 2002
There has been a widespread impression that tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) mediate the toxicity of high doses of lipopolysaccharide (LPS, endotoxin) and are key factors in septic shock. However, the clinical efficacy of treatment with antagonists of TNF-alpha and IL-1beta is still controversial, suggesting that
Wen-Hui, Fang +6 more
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There has been a widespread impression that tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) mediate the toxicity of high doses of lipopolysaccharide (LPS, endotoxin) and are key factors in septic shock. However, the clinical efficacy of treatment with antagonists of TNF-alpha and IL-1beta is still controversial, suggesting that
Wen-Hui, Fang +6 more
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Investigating the Effect of 5’ and 3’ UTRs on mRNA Mobility in Plants
In tomato rootstock and Nicotiana benthamiana heterografting systems, N. benthamiana scions show stress and defense-related transcripts derived from tomato rootstock. tRNA-like and poly-pyrimidine sequences in mRNA untranslated regions (UTRs) may facilitate mRNA mobility.Lin, Judith, Koretsky, Michael
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Biology of reproduction, 2016
Maternal mRNAs in oocytes are remarkably stable. In mouse, oocyte maturation triggers a transition from mRNA stability to instability. This transition is a critical event in the oocyte-to-embryo transition in which a differentiated oocyte loses its identity as it is transformed into totipotent blastomeres.
Jun, Ma +2 more
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Maternal mRNAs in oocytes are remarkably stable. In mouse, oocyte maturation triggers a transition from mRNA stability to instability. This transition is a critical event in the oocyte-to-embryo transition in which a differentiated oocyte loses its identity as it is transformed into totipotent blastomeres.
Jun, Ma +2 more
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mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Nature Reviews Drug Discovery, 2021Namit Chaudhary, Kathryn A Whitehead
exaly
Plant Physiology
Abstract Mobile messenger RNAs (mRNAs) serve as crucial long-distance signaling molecules, responding to environmental stimuli in plants. Although many mobile transcripts have been identified, only a limited subset has been characterized as functional long-distance signals within specific plant species, raising an intriguing question ...
Xiaojun Li +9 more
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Abstract Mobile messenger RNAs (mRNAs) serve as crucial long-distance signaling molecules, responding to environmental stimuli in plants. Although many mobile transcripts have been identified, only a limited subset has been characterized as functional long-distance signals within specific plant species, raising an intriguing question ...
Xiaojun Li +9 more
openaire +2 more sources
Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression
Nature Reviews Molecular Cell Biology, 2021Lori Anne Passmore, Jeff Coller
exaly