Results 31 to 40 of about 2,036,475 (297)

Analysis and operational challenges of dynamic ride sharing demand responsive transportation models [PDF]

open access: yes, 2016
There is a wide body of evidence that suggests sustainable mobility is not only a technological question, but that automotive technology will be a part of the solution in becoming a necessary albeit insufficient condition.
Barceló Bugeda, Jaime   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Preventing Overturning of Mobile Cranes Using an Electrical Resistivity Measurement System

open access: yesApplied Sciences
Mobile cranes are essential for transporting heavy materials at construction sites, but their operation carries significant safety risks, particularly due to the potential for overturning accidents.
Hongseok Jang   +5 more
doaj   +1 more source

Impact of Mobility on the Sum Rate of NB-OFDMA Based Mobile IoT Networks

open access: yes, 2016
In future Internet of Things (IoT) networks, the explosive growth of mobile devices compel us to reconsider the effectiveness of the current frequency-division multiple access (FDMA) schemes.
Jiao, Chunxu   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Towards supply chain resilience with additive manufacturing: A bibliometric survey

open access: yesSupply Chain Analytics, 2023
Additive manufacturing (AM) is an evolutionary manufacturing technology attracting many firms and governments. Its impact, however, on supply chains remains unexplored.
Abderrahmen Bouchenine   +1 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Three‐dimensional differences in plantar surface shape captured by methods used for custom accommodative insole design

open access: yesJournal of Foot and Ankle Research
Background The patient‐specific shape of custom accommodative insoles for individuals with diabetes provides full foot‐to‐insole contact, offloading areas with high plantar pressures and reducing ulceration risk.
Kimberly A. Nickerson   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Smart mobility: opportunity or threat to innovate places and cities [PDF]

open access: yes, 2015
The concept of the “smart mobility” has become something of a buzz phrase in the planning and transport fields in the last decade. After a fervent first phase in which information technology and digital data were considered the answer for making mobility
Lauwers, Dirk, Papa, Enrica
core   +2 more sources

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