Results 41 to 50 of about 2,036,475 (297)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Interaction-induced negative mobility: realization in a system of two coupled Josephson junctions

, 2010
An overdamped dynamical system, biased by an external constant force, does not exhibit negative mobility. However, when the system is coupled to its copy, negative mobility can arise.
Januszewski, Michał, Łuczka, Jerzy
core   +1 more source

Scattering Mechanisms in a High Mobility Low Density Carbon-Doped (100) GaAs Two-Dimensional Hole System [PDF]

, 2011
We report on a systematic study of the density dependence of mobility in a low-density Carbon-doped (100) GaAs two-dimensional hole system (2DHS). At T= 50 mK, a mobility of 2.6 x 10^6 cm^2/Vs at a density p=6.2 x 10^10 cm^- was measured.
E. F. Schubert, E. H. Hwang, G. A. Csáthy, J. D. Watson, K. W. West, L. N. Pfeiffer, M. J. Manfra, S. Das Sarma, S. Mondal   +8 more
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Design and Performance Evaluation of a Hybrid Flux-Path Limited-Angle Torque Motor

Machines
Torque motors are typically operated within a limited angular range and are widely used in high-precision control applications due to their ability to provide uniform torque throughout the operating region.
Ho-Young Lee, Soon-O Kwon, Min-Ro Park
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A CFD-Based Surrogate for Pump–Jet AUV Maneuvering

Journal of Marine Science and Engineering
Prediction of the maneuvering performance of autonomous underwater vehicles equipped with pump–jet propulsion remains computationally intensive when relying solely on high-fidelity computational fluid dynamics.
Younhee Kwon, Dong-Hwan Kim, Jeonghwa Seo, Hyun Chung   +3 more
doaj   +1 more source

Diverse Mobile System for Location‐Based Mobile Data

Wireless Communications and Mobile Computing, 2018
The value of large amount of location‐based mobile data has received wide attention in many research fields including human behavior analysis, urban transportation planning, and various location‐based services. Nowadays, both scientific and industrial communities are encouraged to collect as much location‐based mobile data as possible, which brings two
Qing Liao, Haoyu Tan, Wuman Luo, Ye Ding
openaire   +2 more sources