Results 61 to 70 of about 2,036,475 (297)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Effect of ammonia and natural gas Co-fueling on combustion and greenhouse gas emissions in a marine diesel engine

Case Studies in Thermal Engineering
This study experimentally investigates the effects of fuel blending strategies on combustion and emission characteristics in a single-cylinder, four-stroke marine diesel engine with natural gas and ammonia.
Gyeongtae Park, Cheolwoong Park, Ilpum Jang, Chansoo Park, Minki Kim, Kyunghoon Kim, Yongrae Kim, Jeongwoo Lee   +7 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Leveraging Bluetooth and GPS Sensors for Route-Level Passenger Origin–Destination Flow Estimation

Sensors
Accurate estimation of passenger origin–destination (OD) matrices is critical for optimizing public transportation systems, yet conventional methods face challenges, such as incomplete alighting data, high infrastructure costs, and privacy concerns. With
Junming Xu, Zhenxing Pan, Cheng Zhang, Xiaoguang Yang   +3 more
doaj   +1 more source

Effective temperature in nonequilibrium steady states of Langevin systems with a tilted periodic potential

, 2004
We theoretically study Langevin systems with a tilted periodic potential. It has been known that the ratio $\Theta$ of the diffusion constant to the differential mobility is not equal to the temperature of the environment (multiplied by the Boltzmann ...
F. Ritort, H. Risken, Kumiko Hayashi, Shin-ichi Sasa   +3 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Education and Social Mobility [PDF]

This paper shows that the design of education policy involves a potential conflict between welfare and social mobility. We consider a setting in which social mobility is maximized under the least elitist public education system, whereas welfare ...
Helmuth Cremer, Philippe De Donder, Pierre Pestieau   +2 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Effects of a 30-min rest with a nap chair on task performance, sleepiness, and neurophysiological measures in men with suspected brain fatigue: a randomized controlled crossover trial

Frontiers in Sleep
BackgroundIt has been suggested that a short nap in the afternoon may improve sleepiness, alertness, and task performance. The present study evaluated the effects of a 30-min rest with a new nap chair on task performance, sleepiness, and ...
Minoru Fujino, Mikio Inoue, Yoshiharu Sonoda, Suminori Kono, Chikako Wakana, Shiro Mawatari, Takehiko Fujino, Takehiko Fujino   +7 more
doaj   +1 more source