Results 31 to 40 of about 41,206 (268)

Transplanted Peripheral Blood Stem Cells Mobilized by Granulocyte Colony-Stimulating Factor Promoted Hindlimb Functional Recovery after Spinal Cord Injury in Mice

Cell Transplantation, 2016
Granulocyte colony-stimulating factor (G-CSF) mobilizes peripheral blood stem cells (PBSCs) derived from bone marrow. We hypothesized that intraspinal transplantation of PBSCs mobilized by G-CSF could promote functional recovery after spinal cord injury.
Hiroshi Takahashi, Masao Koda M.D., Ph.D., Masayuki Hashimoto, Takeo Furuya, Tsuyoshi Sakuma, Kei Kato, Akihiko Okawa, Taigo Inada, Koshiro Kamiya, Mitsutoshi Ota, Satoshi Maki, Kazuhisa Takahashi, Masashi Yamazaki, Chikato Mannoji   +13 more
doaj   +1 more source

L’adhésion des collectivités infra-étatiques aux organisations régionales. Enjeux de la participation des collectivités territoriales françaises d’Amérique dans les organisations régionales de l’espace Amérique-Caraïbe

Études Caribéennes, 2019
The French territorial authorities of the Caribbean-America area (CTFA) benefit from a specific legal regime to promote their integration into their immediate environment.
Karine Galy
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Direct Shear Experimental Study on the Mobilized Dilation Behavior of Granite in Alxa Candidate Area for High-Level Radioactive Waste Disposal

Energies, 2019
Dilation behavior is of great importance for reasonable modeling of the stability of the host rock of the repository for high-level radioactive waste disposal.
Cheng Cheng, Xiao Li, Nengxiong Xu, Bo Zheng   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Mobilized Mohr-Coulomb and Hoek-Brown Strength Parameters during Failure of Granite in Alxa Area in China for High-Level Radioactive Waste Disposal

Energies, 2019
Strength parameters of the host rock is of paramount importance for modelling the behaviors of underground disposal repository of high-level radioactive waste (HLW).
Cheng Cheng, Nengxiong Xu, Bo Zheng
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

"Rischio Sismico e cittí  solidale”: dalla ricostruzione del 1693 all'attualití  tra tecniche, prevenzione, paure e speranze.

GEOmedia, 2020
This paper shortly describes the project started by the Digital Cultural Heritage (DiCultHer) Sicilian Centre in the 2018-2019 school year, to participate in the Week of Digital Cultures in Matera (Italy).
Giuseppe Mussumeci
doaj   +1 more source

Science as a Resource for Territorial and Tourism Development of Mountainous Areas of Chilean Patagonia

Revue de Géographie Alpine, 2022
The region of Aysén, in Chilean Patagonia, is an isolated natural mountainous area, which relies on science for its tourist and territorial development. Project leaders are promoting specific scientific research underway in the territory.
Fabien Bourlon, Yannick Vialette, Pascal Mao   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source