Results 41 to 50 of about 41,206 (268)

Mobility and Protected Areas in the Alps [PDF]

open access: yeseco.mont (Journal on Protected Mountain Areas Research), 2009
Of the 95 million annual tourists estimated in the Alps (confirmed by the Working Group Transport of the Alpine Convention, October 2008), around 80-85% use their private car to reach the desired destination, thus deepening the impact of traffic on man and nature in the Alpine Space.
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

La science comme ressource pour le développement territorial et touristique dans les espaces montagnards de la Patagonie chilienne

open access: yesRevue de Géographie Alpine, 2022
The region of Aysén, in Chilean Patagonia, is an isolated natural mountainous area, which relies on science for its tourist and territorial development. Project leaders are promoting specific scientific research underway in the territory.
Fabien Bourlon   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Aggregate stability and penetration resistance after mobilization of a dystrocohesive Ultisol

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
Evaluation of mobilized soil profiles can provide important information on soil compaction reduction processes. In this context, the objective of this study was to evaluate alterations in soil penetration resistance and the impact on the aggregate ...
Uilka E. Tavares   +5 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Semeadora-adubadora: mecanismos de corte de palha e cargas verticais aplicadas Seedrill: mechanism of culting straw and applied vertical loads

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2012
Realizou-se este trabalho com o objetivo de avaliar o desempenho dos mecanismos de corte de palha de uma semeadora-adubadora em diferentes coberturas vegetais e cargas verticais aplicadas.
Paulo R. A. Silva   +5 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Topographic controls on landslide mobility: modeling hurricane-induced landslide runout and debris-flow inundation in Puerto Rico [PDF]

open access: yesNatural Hazards and Earth System Sciences
In 2017, Hurricane Maria triggered more than 70 000 landslides in Puerto Rico. After initiation, these predominantly shallow landslides were mobilized to varying extents – some landslides only traveled partway downslope, whereas others reached drainage ...
D. L. Brien   +3 more
doaj   +1 more source

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