Results 131 to 140 of about 1,234,147 (346)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Logical consequence in modal logic: Natural deduction in ${\rm S}5$. [PDF]

, 1969
John Corcoran, George Weaver
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Experimental and numerical study on vibration-based damage detection and localisation in laminated composite plates

Fracture and Structural Integrity
Damage detection in composite materials is crucial for ensuring the safety and reliability of engineering structures. Conventional methods often face challenges in accurately identifying damage in plate-like structures, particularly in scenarios ...
Saeesh Verenkar, I. Sridhar, Vinayak S. Uppin, P. S. Shivakumar Gouda   +3 more
doaj   +1 more source

Cross-modal transfer of a specific discrimination in the rabbit [PDF]

, 1969
Arthur L. Yehle, Jeannette P. Ward
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Mekanisme kekerasan simbolik dalam proses pendidikan formal di kota Palu

JPPI (Jurnal Penelitian Pendidikan Indonesia)
Penelitian ini bertujuan untuk mengungkap mekanisme terjadinya kekerasan simbolik pada siswa SD di Kota Palu. Metode penelitian yang digunakan adalah penelitian kualitatif, teknik pengumpulan data melalui observasi, wawancara, dan dokumentasi.
Arif Firmanyah, Juraid Abdul Latief, Indah Ahdiah, Ilyas Lampe, Herlina Herlina, Bau Ratu   +5 more
doaj   +1 more source

On Ł ukasiewicz's ${\rm \L}$-modal system. [PDF]

, 1961
Timothy Smiley
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Cross-modal estimation of angular velocity [PDF]

, 1968
James H. Brown
openalex   +1 more source