Results 131 to 140 of about 1,564,204 (345)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Static and dynamic analysis of different MYSat frame structure
Journal of Mechanical Engineering and SciencesThe development of CubeSats have been advanced following the miniaturization of electronic components. While CubeSats have been extensive used in various missions, most prior research has focused on validating their structural design to comply with ...
Ahmad Shaqeer Mohamed Thaheer +3 more
doaj +1 more source
Topological Modal Logics with Difference Modality
CoRR, 2010 We consider propositional modal logic with two modal operators $\Box$ and $\D$. In topological semantics $\Box$ is interpreted as an interior operator and $\D$ as difference. We show that some important topological properties are expressible in this language. In addition, we present a few logics and proofs of f.m.p. and of completeness theorems.
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Telisik Perlakuan Teori Entitas dalam Usaha Mikro, Kecil dan Menengah (UMKM)
Jurnal Akuntansi Multiparadigma, 2013 Various challenges and obstacles still occur in SMEs development in Indonesia. One of them is the behavior of SMEs owners who often do not separate personal finance and business capital.
Dian Purnama Sari
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Sound Radiation Analysis and Noise Reduction Design of Railway Wheel
机车电传动, 2018 The wheel radiation noise is an important contributor of railway noise. Based on the acoustic simulation and experimental techniques, this paper analyzed the radiation noise characteristics of a wheel, and designed a noise reduction wheel combined with ...
ZHA Guotao +4 more
doaj