Results 181 to 190 of about 2,484,152 (338)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Structure Analysis and Optimization of DGMC-16 Rail Grinding Wagon Frame

机车电传动, 2016
Taking the frame of DGMC-16 rail grinding wagon as studying object, the finite element method was adopted to calculate the longitudinal loads, judge the weak locations of frame for local optimization, and calculate the strength under different operation ...
Deng Ting, Zhu Shichang, Huang Zhihui, Zhang Linghong   +3 more
doaj  

Multi-Modal Sensing M2M Healthcare Service in WSN [PDF]

, 2012
Wan-Young Jung
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Modal response characterizations and mechanism separation modeling of amphibious vehicle body under different water entry depths. [PDF]

iScience
Li G, Bao K, Wang W, Zuo Z, Han Z, Zhao C, Wang H.   +6 more
europepmc   +1 more source

Examining the Effects of Immersive and Non-Immersive Presenter Modalities on Engagement and Social Interaction in Co-located Augmented Presentations [PDF]

Matt Gottsacker, Mengyu Chen, David Saffo, Feiyu Lu, Benjamin Lee, Blair MacIntyre   +5 more
openalex   +1 more source

The Effect of the Modality on Students’ Computational Thinking, Programming Attitude, and Programming Achievement

, 2023
İbrahim Çetin, Tarık OTU
openalex   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Cross-modal dual-domain bi-direction feature interaction network for medical imaging semantic segmentation. [PDF]

Sci Rep
Zhou T, Liu Q, Song K, Chai W, Chen K, Lu H.   +5 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source