Results 91 to 100 of about 21,974 (265)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Structural model updating and prediction variability using Pareto optimal models [PDF]

open access: yes, 2008
A multi-objective identification method for structural model updating based on modal residuals is presented. The method results in multiple Pareto optimal structural models that are consistent with the experimentally measured modal data and the modal ...
Konstantinos Christodoulou (7175594)   +11 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Operational Modal Analysis for Seismic Protection of Structures

open access: yes, 2008
This thesis focuses on output-only modal identification tests and on the opportunities they provide in the field of seismic protection of structures. The problem of a good measurement process, in order to obtain high quality data and reliable results ...
Rainieri, Carlo
core  

Time–Frequency Analysis of Railway Bridges Forced and Free Vibrations Identified by Wavelet Transform

open access: yesVibration
In this work, a time–frequency analysis of two railway bridges included in the InBridge4EU project database is presented. The study focuses on the identification of modal parameters from free responses after train passages and their comparison with ...
Pedro Galvín   +4 more
doaj   +1 more source

Identification of modal parameters for complex structures by experimental modal analysis approach

open access: yesAdvances in Mechanical Engineering, 2016
In this research, we have proposed a methodology for experimental identification of modal parameters based on measurement of the frequency responses of structures with complex geometries and performed an overall investigation of structural behavior on a ...
Tamara Nestorović   +2 more
doaj   +1 more source

Experimental Validation of Modal Parameters in Rotating Machinery [PDF]

open access: yes
In this paper, instability of rotating machinery systems due to rotating damping is investigated through experimental modal analysis. Generally, advanced methods are needed for these kind of systems because of the asymmetry of the matrices. However, it is shown by means of cyclic energy dissipation that the rotating damping can be handled as damping ...
Vervisch, Bram   +2 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Ability of modal analysis to detect osseointegration of implants in transfemoral amputees : a physical model study

open access: yes, 2013
Owing to the successful use of non-invasive vibration analysis to monitor the progression of dental implant healing and stabilization, it is now being considered as a method to monitor femoral implants in transfemoral amputees.
Cairns, Nicola   +3 more
core   +1 more source

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