Results 51 to 60 of about 18,427 (298)

Adversarial reconstruction for Multi-modal Machine Translation

CoRR, 2019
Even with the growing interest in problems at the intersection of Computer Vision and Natural Language, grounding (i.e. identifying) the components of a structured description in an image still remains a challenging task. This contribution aims to propose a model which learns grounding by reconstructing the visual features for the Multi-modal ...
Delbrouck, Jean-Benoit, Dupont, Stéphane   +1 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Modal Shapes Selection Criterion for Modal Reconstruction Aimed at Structural Health Monitoring

Engineering Proceedings
This paper aims to demonstrate the applicability of a modal selection criterion based on strain energy potential for describing static deformations in a commonly used engineering geometry, specifically a circular plate. The analytical model relies on the
Gabriele Liuzzo, Miriam Parisi, Pierluigi Fanelli   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Analytical Formulation of New Mode Selection Criteria in the Reconstruction of Static Deformation of Structures Through Modal Superposition

Applied Mechanics
The accuracy of modal superposition methods for determining displacement or strain field of structures largely depends on the selection of modes relevant to its deformation. Analytical methods for modal selection have been developed to minimise errors in
Gabriele Liuzzo, Miriam Parisi, Pierluigi Fanelli   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

CrossAlignNet: a self-supervised feature learning framework for 3D point cloud understanding [PDF]

PeerJ Computer Science
We propose a self-supervised point cloud representation learning framework CrossAlignNet based on cross-modal mask alignment strategy, to solve the problems of imbalance between global semantic and local geometric feature learning, as well as cross-modal
Fei Wang, Xingzhen Dong, Jia Wu, Weishi Zhang, Tuo Zhou   +4 more
doaj   +2 more sources

Semi-Lexical Heads in Czech Modal Structures [PDF]

, 2008
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyThis thesis argues for a semi-lexical interpretation of Czech modal verbs. It demonstrates that Czech modals participate
Kyncl, Jaroslav
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Structural Shape Reconstruction of FBG Flexible Plate Using Modal Superposition Method

, 2017
Structural shape reconstruction is a critical issue for real-time structural health monitoring in the fields of engineering application. This paper shows how to implement structural shape reconstruction using a small number of strain data measured by ...
Zi Y. Geng, Wei Sun, Ben S. Zhong, Li Li
core   +1 more source