Results 41 to 50 of about 22,495 (265)
Shock and Vibration, 2000 This paper deals with the formulation of a frequency domain modal analysis technique that is applicable to weakly non-linear multi-degree of freedom (MDOF) systems with well-separated modes.
Y.H. Chong, M. Imregun
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
GENERATIVE ADVERSARIAL NETWORKS (GANs) IN MULTIMODAL AI USING BRIDGING TEXT, IMAGE, AND AUDIO DATA FOR ENHANCED MODEL PERFORMANCE [PDF]
ICTACT Journal on Soft ComputingThe integration of multimodal data is critical in advancing artificial intelligence models capable of interpreting diverse and complex inputs. While standalone models excel in processing individual data types like text, image, or audio, they often fail ...
R. Arun Kumar +3 more
doaj +1 more source
Differentiated haptic stimulation by modal synthesis of vibration field [PDF]
2018 IEEE Haptics Symposium (HAPTICS), 2018 To date, Several focusing techniques have been proposed to realize localized stimulation on haptic interfaces: phased arrays of actuators with delayed excitation, or time reversal techniques which require a preliminary learning phase. Additionally, these techniques are sensitive to parameters variation and disturbances.
Ehsan Enferad +4 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Maximal Synthesis for Hennessy-Milner Logic with the Box Modality [PDF]
IFAC Proceedings Volumes, 2014 This paper presents a novel approach to adapt a behavioral model in order to satisfy a requirement in Hennessy-Milner Logic, including an additional box modality operator, expressing an invariant formula. Control system synthesis, as defined in this way, retains all non-invalidating behavior, and thereby guarantees maximal permissiveness for ...
Allan van Hulst +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source