Results 61 to 70 of about 22,495 (265)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Bessel and cosine filtering approaches for electromechanical modes identification

International Journal of Electrical Power & Energy Systems
The real-time system monitoring of electromechanical oscillations in power grids is essential to maintain operational control in an optimal state and to make the right decisions in any adverse situation.
Rodrigo David Reyes de Luna, José Antonio de la O Serna, Mario R. Arrieta Paternina, Alejandro Zamora-Mendez, Antonino López-Rios   +4 more
doaj   +1 more source

Structural Synthesis for Prescribed Target Natural Frequencies and Mode Shapes

Shock and Vibration, 2014
A new method for the synthesis of structures with prescribed target natural frequencies and mode shapes is presented. The introduction of a modal Rayleigh quotient approximation based on the target mode shapes is the means to propose a structural ...
J. A. Hernandes, A. Suleman
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Joint Camera-LiDAR Scene Synthesis and Perception for Autonomous Driving

IEEE Access
The advancement of autonomous driving and embedded AI systems has intensified the need for large-scale, richly annotated multimodal datasets encompassing RGB images, semantic labels, and 3D LiDAR data.
S. Raghavendra, S. K. Abhilash, Venu Madhav Nookala, P. V. Arun Kumar, B. N. Anoop, Ramyashree   +5 more
doaj   +1 more source

Multi-modal Contrastive Learning for Tumor-specific Missing Modality Synthesis

CoRR
Multi-modal magnetic resonance imaging (MRI) is essential for providing complementary information about brain anatomy and pathology, leading to more accurate diagnoses. However, obtaining high-quality multi-modal MRI in a clinical setting is difficult due to factors such as time constraints, high costs, and patient movement artifacts.
Minjoo Lim, Bogyeong Kang, Tae-Eui Kam
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

STUDY ON FREE VIBRATION ANALYSIS FOR HONEYCOMB SANDWICH STRUCTURE WITH DOUBLE CORES

Jixie qiangdu, 2018
The free vibration problem of the honeycomb sandwich structure with double cores was studied based on the Layerwise/Solid-Elements（ LW/SE） and Fixed-interface Modal Synthesis Technique（ FMST） of the dynamic substructure method. The governing equation and
LU Xiang, YANG JiuYue, WANG RuiPeng, QIAN RuoLi   +3 more
doaj