Results 101 to 110 of about 84,248 (219)
Jixie chuandong, 2014 Modal analysis of the rolling-sliding compound bearing is carried out by using ABAQUS.It is shows that the theoretical values of the natural frequency and vibrational modes are well consistent with that obtained in FEM of bearing inner ring.The basic ...
卢黎明, 秦豫江, 蔡颖
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Modal Analysis of the 450T Offshore Derrick and Recommendations for Drilling
Shiyou jixie, 2015 The derrick will resonate when its natural frequency closes to or coincides with the vibration frequencies of external device and wind load.The theory of modal analysis is introduced.Dynamic analysis on the 450T offshore derrick has been conducted using ...
Wu Wenxiu +4 more
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Multimodal subspace independent vector analysis effectively captures latent relationships between brain structure and function. [PDF]
Imaging Neurosci (Camb)Li X +4 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
EMP: Enhanced Multi-modal Prediction for fashion sales using Fourier Mapping and ERP-based contrastive learning. [PDF]
PLoS OnePark S, Park B, Lee S, Shin S, Kim W.
europepmc +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
SIM-PCSR: Key-Layer Complementary Enhancement for UAV RGB-IR Small-Object Detection. [PDF]
Sensors (Basel)He J, Yang Y, Li J.
europepmc +1 more source