Results 131 to 140 of about 505,512 (306)
Coupled rotor/airframe vibration analysis [PDF]
A coupled rotor/airframe vibration analysis developed as a design tool for predicting helicopter vibrations and a research tool to quantify the effects of structural properties, aerodynamic interactions, and vibration reduction devices on vehicle ...
Cassarino, S. +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Many-valued logics and Suszkian modalities
, 2022 In this paper, we investigate the family LS0.5 of many-valued modal logics LS0.5's. We prove that the modalities of necessity and possibility of the logics LS0.5's capture well-defined bivalent concepts of logical validity and logical consistency. We also show that these modalities can be used as recovery operators.
Bezerra E, Venturi G
openaire +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Discover DataBreast cancer prognosis prediction is pivotal to improving the survival chances of breast cancer patients. Recently, deep learning models integrated with multi-modal data have been explored extensively to improve the reliability and accuracy of breast ...
Shamita Uma Kandan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Reduction of Many-valued into Two-valued Modal Logics
, 2011 In this paper we develop a 2-valued reduction of many-valued logics, into 2-valued multi-modal logics. Such an approach is based on the contextualization of many-valued logics with the introduction of higher-order Herbrand interpretation types, where we explicitly introduce the coexistence of a set of algebraic truth values of original many-valued ...
openaire +2 more sources
Structural characterization of a first-generation articulated-truss joint for space crane application [PDF]
A first-generation space crane articulated-truss joint was statically and dynamically characterized in a configuration that approximated an operational environment.
Laufer, Joseph B. +4 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source