Results 51 to 60 of about 1,622 (214)
In defense of the possibilism–actualism distinction [PDF]
, 2020 In Modal Logic as Metaphysics, Timothy Williamson claims that the possibilism-actualism (P-A) distinction is badly muddled. In its place, he introduces a necessitism-contingentism (N-C) distinction that he claims is free of the confusions that ...
Menzel, Christopher
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Reflexii ale modernității muzicale în creațiile timpurii ale lui Zeno Vancea
Symbolon, 2019 Reflections of Musical Modernity in Zeno Vancea's Early Creations The paper aims to present the activity and creation of composer and teacher Zeno Vancea during his youth when he worked at the Conservatory in Târgu Mureș.
Mirela Mercean-Ţârc
doaj
Ignoring God Triune? The Doctrine of the Trinity in Dutch Theology [PDF]
, 2009 Contains fulltext : 82094.pdf (publisher's version ) (Closed ...
Brink, G. van den, Erp, Stephan van
core +4 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
An Episodic Account of Divine Personhood [PDF]
I present Ned Markosian's episodic account of identity under a sortal, and then use it to sketch a new model of the Trinity. I show that the model can be used to solve at least three important Trinitarian puzzles: the traditional ‘logical problem of the ...
Mooney, Justin
core
A problem-structuring model for analyzing transportation–environment relationships [PDF]
, 2010 This is the post-print version of the final paper published in European Journal of Operational Research. The published article is available from the link below.
Anderson +51 more
core +1 more source
MODAL: A multilingual corpus annotated for modality [PDF]
, 2017 We have produced a corpus annotated for modality which amounts to approximately 20,000 words in English, French, and Italian. The annotation scheme is based on the notion of epistemic construction and virtually languageindependent. The annotation is rigorously evaluated by means of a newly developed strategy based on the alignment of the entire ...
Nissim, Malvina, Pietrandrea, Paola
openaire +3 more sources
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source