Results 11 to 20 of about 534,974 (269)

Valuation Сomponent of Metaphor UP vs. DOWN in German Political Cartoon

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2021
In German political cartoon the metaphor UP vs. DOWN introduces oppositions GOOD vs. BAD, MORE vs. LESS, UNREALIZABLE vs. PRACTICABLE. The paper describes their valuation components accenting the positive or negative sign of oppositions and its base in ...
Galina L. Denisova
doaj   +1 more source

Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities

open access: yesScientific Reports, 2017
Single domain antibodies (sdAbs), made of natural single variable regions of camelid or cartilaginous fish antibodies, or unpaired variable regions of mouse or human IgGs, are some of the more promising biologic modalities.
Naoya Shinozaki   +3 more
doaj   +1 more source

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

open access: yesFrontiers in Immunology, 2020
Interleukin (IL)-17A is a key driver of inflammation and the principal target of anti-IL-17 therapeutic monoclonal antibodies. IL-17A, and its structurally similar family member IL-17F, have been shown to be functionally dysregulated in certain human ...
Ralph Adams   +10 more
doaj   +1 more source

Spatially compounded plane wave imaging using a laser-induced ultrasound source

open access: yesPhotoacoustics, 2020
This work presents spatially compounded plane wave imaging using a laser-induced ultrasound source. The plane wave source consisted of a 30 μm thick film of carbon black-doped PDMS cured on a 100 μm thick polyester substrate and presented a rectangular ...
David Thompson   +2 more
doaj   +1 more source

Modal auxiliary verb constructions in East African Bantu languages

open access: yesJournal of African Languages and Literatures, 2022
In this article we offer an overview of the use of modal auxiliary verb constructions in East African Bantu (encompassing languages spoken from eastern Congo in the north-west to northern Mozambique in the south-east; viz.
Rasmus Bernander   +2 more
doaj   +1 more source

Polygrammaticalization of the verb "xāstan" in Persian Language A cognitive study in the framework of basic event schemas [PDF]

open access: yes̒Ilm-i Zabān, 2020
Polygrammaticalization is a type of multiple development where a single form develops distinct grammatical functions in different constructions. The verb ‘xāstan’ is an instance of this phenomenon which conceptualizes specific notions of tense, aspect ...
Morteza Dastlan
doaj   +1 more source

Ex-Vivo Human-Sized Organ Machine Perfusion: A Systematic Review on the Added Value of Medical Imaging for Organ Condition Assessment

open access: yesTransplant International
Machine perfused ex-vivo organs offer an excellent experimental platform, e.g., for studying organ physiology and for conducting pre-clinical trials for drug delivery. One main challenge in machine perfusion is the accurate assessment of organ condition.
Jan L. Van Der Hoek   +4 more
doaj   +1 more source

Current and future trends in photoacoustic breast imaging

open access: yesPhotoacoustics, 2019
Non-invasive detection of breast cancer has been regarded as the holy grail of applications for photoacoustic (optoacoustic) imaging right from the early days of re-discovery of the method.
Srirang Manohar, Maura Dantuma
doaj   +1 more source

Phonological development in American Sign Language-signing children: Insights from pseudosign repetition tasks

open access: yesFrontiers in Psychology, 2022
In this study, we conducted a pseudosign (nonce sign) repetition task with 22 children (mean age: 6;04) acquiring American Sign Language (ASL) as a first language (L1) from deaf parents.
Shengyun Gu   +3 more
doaj   +1 more source

The Study of the Emergence of Modal Functions of the Verb “Residan” (to arrive) in Persian from the Perspective of Grammaticalization [PDF]

open access: yes̒Ilm-i Zabān, 2020
Modal functions of the verb “residan” (to arrive) and the emergence of such modal characteristics are discussed from the perspective of grammaticalization in the present study.
Mahmood Jafari Dehaghi   +2 more
doaj   +1 more source

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