Results 31 to 40 of about 340,881 (244)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Conceivability, Apriority and Modality [PDF]

, 2011
I aim to understand whether apriority entails necessity, aposteriority entails contingency and conceivability entails possibility; that is, the relationship between, and the nature of, rationality and modality.
WINSTANLEY, PAUL
core  

Dynamic contrast-enhanced ultrasound predicts microsphere biodistribution in real-time during transarterial radioembolization

Communications Medicine
Background Transarterial radioembolization (TARE) treatment efficacy critically depends on the microsphere biodistribution in the liver. Current treatment planning protocols rely on a pre-treatment scout procedure to evaluate this biodistribution for a ...
J. L. van der Hoek, T. J. Snoeijink, A. Visser, K. D. E. de Bree, M. E. Krommendijk, J. G. M. Greve, H. R. Liefers, W. M. Brink, M. Versluis, J. Arens, S. Manohar, E. Groot Jebbink   +11 more
doaj   +1 more source

Spatially compounded plane wave imaging using a laser-induced ultrasound source

Photoacoustics, 2020
This work presents spatially compounded plane wave imaging using a laser-induced ultrasound source. The plane wave source consisted of a 30 μm thick film of carbon black-doped PDMS cured on a 100 μm thick polyester substrate and presented a rectangular ...
David Thompson, Damien Gasteau, Srirang Manohar   +2 more
doaj   +1 more source

Localizing Violations of the Principle of Sufficient Reason—Leibniz on the Modal Status of the PSR

Journal of Modern Philosophy, 2022
The Principle of Sufficient Reason (PSR)—the principle that everything has a reason—plays a central role in Leibniz’s philosophical system. It is rather difficult, however, to determine what Leibniz’s attitude towards the modal status of the PSR is.
Sebastian Bender
doaj   +1 more source

What Modals Are: Modal Verbs, Modal Words, and Auxiliary Modals

European Researcher, 2013
The modals are a complicated grammatical phenomenon. As of today, the status of modals is still not precisely defined in the linguistics literature, and they are described under different names: modal verbs, modal words, auxiliary modals, or defective verbs.
openaire   +1 more source

Diagnostic Modalities

International Journal of Surgery, 2016
The incidental detection of small renal masses on imaging undertaken to evaluate unrelated symptoms or conditions is an increasingly common occurrence. Accurate imaging characterisation is fundamental to determining optimum patient management. The goals of imaging small renal masses include determining whether a lesion is solid or cystic, if there are ...
Alison, Elstob, Michael, Gonsalves, Uday, Patel   +2 more
openaire   +2 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Upright and supine assessment of pelvic floor muscle defects in women with and without prolapse

Scientific Reports
The levator ani muscle (LAM), crucial for pelvic organ support, can develop defects that contribute to pelvic floor disorders (PFD) like pelvic organ prolapse (POP). Factors such as childbirth, aging, and menopause increase the risk of LAM damage.
Irina de Alba Alvarez, Frieda van den Noort, Frank F.J. Simonis, Anique T.M. Grob   +3 more
doaj   +1 more source

Current and future trends in photoacoustic breast imaging

Photoacoustics, 2019
Non-invasive detection of breast cancer has been regarded as the holy grail of applications for photoacoustic (optoacoustic) imaging right from the early days of re-discovery of the method.
Srirang Manohar, Maura Dantuma
doaj   +1 more source