Results 91 to 100 of about 8,188,078 (300)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Distinction of Attributes, The Unification of Modes: Reconsidering an interpretive controversy concerning the nature of Attributes in Spinoza's Philosophy [PDF]

open access: yesحکمت و فلسفه
One of the challenges faced by Spinoza's commentators is the problem of the nature of attributes; That is, the answer to the question of whether attributes are distinct from the substance (objective interpretation) or not (subjective interpretation). The
Zahra Amini, Mustafa Zali
doaj   +1 more source

The Beauty of Symmetry: Common-mode rejection filters for high-speed interconnects and balanced microwave circuits [PDF]

open access: yes, 2017
Common-mode rejection filters operating at microwave frequencies have been the subject of intensive research activity in the last decade. These filters are of interest for the suppression of common-mode noise in high-speed digital circuits, where ...
Bonache, Jordi   +6 more
core  

Nuclear Scissors Mode with Pairing

open access: yes, 2007
The coupled dynamics of the scissors mode and the isovector giant quadrupole resonance are studied using a generalized Wigner function moments method taking into account pair correlations.
A. Bohr   +38 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The BELLFLOW system [PDF]

open access: yes, 1970
The BELLFLOW flowcharting system was developed to meet certain Bell System standards of documentation. There are three modes of operation with the BELLFLOW system: source mode, comment mode, and mixed mode.
Pardee, S.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Multipole-mode surface solitons

open access: yes, 2006
We discover multipole-mode solitons supported by the surface between two distinct periodic lattices imprinted in Kerr-type nonlinear media. Such solitons are possible because the refractive index modulation at both sides of the interface glues together ...
Chen   +23 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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