Results 101 to 110 of about 8,188,078 (300)

‘I’m grown a man no doubt, I’ve broken bounds’—Robert Browning Crossing the Limits of Poetry

open access: yesCahiers Victoriens et Edouardiens, 2016
This paper will focus on Robert Browning’s poetic writings, and especially on the way his poems were a constant crossroads of formal choices, from his very first publications to his last poem.
Jean-Charles Perquin
doaj   +1 more source

Update on g-mode research

open access: yes, 2008
Since the beginning of this century we have attended a blooming of the gravity-mode research thanks to the unprecedented quality of the data available, either from space with SoHO, or from the ground-based networks as BiSON or GONG.
Appourchaux   +37 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Sustaining Science Infrastructure Is Difficult; Is Commercialization the Answer? The USA National Phenology Network's Experience

open access: yesPerspectives of Earth and Space Scientists
Biological and physical science infrastructure programs play a critical role in supporting scientific discovery. Even with their foundational roles in the process of science, frequently, support for these programs is threatened, reduced, or eliminated ...
T. M. Crimmins, J. Clark
doaj   +1 more source

Perception of Western Musical Modes: A Chinese Study

open access: yesFrontiers in Psychology, 2017
The major mode conveys positive emotion, whereas the minor mode conveys negative emotion. However, previous studies have primarily focused on the emotions induced by Western music in Western participants. The influence of the musical mode (major or minor)
Lele Fang   +5 more
doaj   +1 more source

Edge modes without edge modes

open access: yes, 2021
We discuss gauge theories of the Yang-Mills kind in finite regions with boundaries, and in particular the definition of the corresponding quasi-local degrees of freedom and their gluing upon composition of the underlying regions. Although the most of the technical results presented here has appeared in previous works by Gomes, Hopfm ller and the ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Mode of Computing

open access: yes, 2019
The Turing Machine is the paradigmatic case of computing machines, but there are others, such as Artificial Neural Networks, Table Computing, Relational-Indeterminate Computing and diverse forms of analogical computing, each of which based on a ...
Pineda, Luis A.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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