Results 121 to 130 of about 3,718,699 (318)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Research progress on continuous nursing model of stroke patients
Huli yanjiu, 2018 It reviewed the research progress on continuous nursing mode of stroke patients from the concept of continuous nursing,the concept of continuous nursing service for stroke,service object,provider,intervention strategy,nursing measures,application effect ...
朱伟, 蒋艳
doaj
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2011 Mode bukan sekadar urusan gaya atau busana semataMode adalah bisnis...Mode adalah industriKamus Mode Indonesia merupakan buku referensi yang memuat lebih dari 1600 istilah mode berikut arti, definisi, maupun deskripsinya yang disusun secara alfabetik ...
Ninuk Mardiana Pambudy +3 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Thermodynamic Basis for Predicting Falling-Film Mode Transitions
, 2012 Horizontal-tube, falling-film heat exchangers are used in many air-conditioning and refrigeration systems. Depending on the geometry, flow rate and fluid properties, when a liquid film falls over a series of horizontal tubes several distinct flow ...
Jacobi, Anthony M., Wang, Xiaofei
core
Large mode area pixelated trench fiber
, 2014 We propose a novel fiber that offers excellent suppression of higher-order-modes with loss higher than 10dB/m and low loss for fundamental mode (<0.1dB/m) at 1.06µm, with effective area as large as 1100µm2 and excellent bend ...
Baskiotis, C. +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Akademik İncelemeler Dergisi, 2014 Türk halk müziğinin en önemli problemlerinden birisi terminolojidir. Bu problemlerin başında ise, Türk Halk Müziğinin melodik veya ezgisel yapısının adlandırılması konusu gelmektedir.
Savaş Ekici
doaj