Results 131 to 140 of about 3,718,699 (318)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Single-mode fiber length for wavefront filtering

, 2008
Stellar nulling interferometry offers the possibility of direct imaging of extrasolar planets necessary for the detection of extra-terrestrial life. Achieving optimum performance from the interferometers requires that the wavefronts of light reaching the
Dasgupta, Sonali, Broderick, N.G.R., Richardson, D.J.   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Parution: L'Art de la mode, Catherine Örmen

, 2015
Éditions Citadelles&Mazenod, Une approche historique et esthétique du XVIIIe siècles à nos jours avec 600 illustrations (costume, textile, illustrations et photographies de mode) Catherine Örmen viendra présenter son ouvrage le 22 janvier au #SemMode!
Sophie Kurkdjian
core  

Rethinking context: realisation, instantiation, and individuation in systemic functional linguistics

Journal of World Languages
In spite of decades of research developing a model of language and context, there is little consensus in systemic functional linguistics (SFL) about how context should be modelled and how language and context are related.
Doran Y. J., Martin J. R., Herrington Michele   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Gain equalization of a six-mode-group ring core multimode EDFA

We propose a 6-mode-group ring core multimode erbium doped fiber amplifier (RC-MMEDFA) capable of providing almost identical gain among the six mode groups within the C band using either core- or cladding-pumped ...
Alam, S.U., Lim, E.L., Jin, X., Jung, Y., Kang, Q., Richardson, D.J., Payne, F.P.   +6 more
core  

Forum de la mode 2 - Le sens de la mode _ 10 novembre 2017

, 2017
La deuxième édition du Forum de la Mode se tient à Bercy le vendredi 10 novembre 2017 sous le titre "Le sens de la mode". Bruno Le Maire, ministre de l'Économie et des Finances, et Françoise Nyssen, ministre de la Culture, participeront au "Forum
Sophie Kurkdjian
core  

En mode modes !

Caramel, 2023
openaire   +2 more sources