Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
8ème séance du séminaire sur la mode, "Mode et images", 23 mai 2014, 14h30-17h30
Nous aurons le plaisir d'écouter les interventions suivantes: -Corinne Thépaut-Cabasset, historienne de l’art et de la mode, chargée de recherche au château de Versailles, et chercheur associé (2010-2013) au Victoria and Albert Museum "La mode en images ...
Sophie Kurkdjian
core
Default-mode network activity is retained in the isolated hemisphere of people after hemispherotomy. [PDF]
Bauer T +10 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Modal Superposition-Induced Novel Directional Responses in a Low-Damping Biomimetic Microphone for Sound Source Localization. [PDF]
Ren D, Yang X, Qi ZM.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
"La mode, un secteur dominé par l’homme"
http://www.lemonde.fr/m-mode-business-of-fashion/article/2016/10/11/la-mode-un-secteur-domine-par-l-homme_5011837_4497393 ...
Sophie Kurkdjian
core
Beyond Random Splits: Assessing the Generalization of Graph and Vector Models for WT-Structure-Only Drug Resistance Prediction under Protein-Disjoint Evaluation. [PDF]
Cheng Z, Wu H, Ming D.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Study of Asymmetric Test Configurations by Means of Standard and Revised Virtual Crack-Closure Techniques. [PDF]
Bonhomme J, Mollón V.
europepmc +1 more source

