Results 61 to 70 of about 8,588 (301)

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

Mode division multiplexed optical transmission enabled by all–fiber mode multiplexer

Optics Express, 2014
Mode division multiplexed optical transmission enabled by all-fiber mode multiplexer is investigated. The proposed all-fiber mode multiplexer is composed of consecutive mode selective couplers. It multiplexes or demultiplexes LP01, LP11, LP21, and LP02 modes simultaneously. We demonstrate successful transmission of three spatial modes with 120 Gb/s PDM-
Chang, Sun Hyok, Chung, Hwan Seok, Fontaine, Nicolas K., Ryf, Roland, Park, Kyung Jun, Kim, Kwangjoon, Lee, Jyung Chan, Lee, Jong Hyun, Kim, Byoung Yoon, Kim, Young Kie   +9 more
openaire   +4 more sources

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

Advanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon, Ali Tufani, Süleyman Çelik, Javed H. Niazi, Anjum Qureshi   +4 more
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Integrated silicon multifunctional mode-division multiplexing system.

Optics Express, 2019
Chip-scale optical interconnects have been widely investigated using the wavelength-division multiplexing (WDM) technology, while it has been rarely reported using the mode-division multiplexing (MDM) technology that further improves communication ...
De Zhou, Chunlei Sun, Yaxiao Lai, Yu Yu, Xinliang Zhang   +4 more
semanticscholar   +1 more source

Reconfigurable Three-Mode Converter for Flexible Mode Division Multiplexing Optical Networks

IEEE Photonics Journal
Mode converters with reconfigurable functionality are essential for enabling flexible operation in modern mode division multiplexing (MDM) technology-based optical networks. In this paper, we propose a novel reconfigurable three-mode converter capable of
Mohammad Shuhrawardy, Kazi Tanvir Ahmmed, Chi Hung Yeung, Wei Jin, Liangjun He, Binghui Li, Hau Ping Chan   +6 more
doaj   +1 more source

Simultaneous Wavelength- and Mode-Division (De)multiplexing for High-Capacity On-Chip Data Transmission Link

IEEE Photonics Journal, 2016
We present designs of wavelength-division-multiplexing (WDM) and mode-division-multiplexing (MDM) optical links using mode de/multiplexers (DE/MUXs) based on multimode interference (MMI) couplers with a tilt joint as a phase shifter.
Liangshun Han, Song Liang, Junjie Xu, Lijun Qiao, Hongliang Zhu, Wei Wang   +5 more
doaj   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source