Results 81 to 90 of about 7,768 (254)

T-shaped mode coupler for two-mode mode division multiplexing

open access: yesIEICE Electronics Express, 2011
We propose a novel type of mode coupler consisting of two identical rectangular few-mode waveguides with different orientations. Numerical simulation indicates that mode extinction ratio exceeding 20dB can be achieved by well-aligned waveguides.
Hirokazu Kubota   +2 more
openaire   +2 more sources

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

Effect of decision feedback equalizer taps on 3×6- channel mode-wavelength division multiplexing system performance in multimode fiber

open access: yesEPJ Web of Conferences, 2017
In this paper, the effect of tap configurations in a decision feedback equalizer is investigated for controlling modal dispersion in a 60Gb/s 18-channel mode division multiplexing - wavelength division multiplexing system in a 2.5km multimode fiber on ...
Masunda Tendai   +2 more
doaj   +1 more source

An N-Port Universal Multimode Optical Router Supporting Mode-Division Multiplexing. [PDF]

open access: yesMicromachines (Basel), 2021
Yang Y   +8 more
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

Multi-gas photoacoustic sensor using multi-mode demodulation

open access: yesPhotoacoustics
Modulation technology is the necessary means for generating periodic acoustic waves in photoacoustic gas detection, primarily including intensity modulation and wavelength modulation.
Mu Liang   +7 more
doaj   +1 more source

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