Results 41 to 50 of about 430 (135)

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, Volume 13, Issue 18, 27 March 2026.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Low-Crosstalk High-Order Mode Silicon Fiber-Chip Coupler by Utilizing Apodized Double Part Gratings With Mode Selective Trident

IEEE Photonics Journal, 2023
We propose and experimentally demonstrate a silicon integrated high-order mode fiber-chip coupler. By utilizing a structure of apodized double-part gratings with mode selective trident, TE1 mode can be coupled with low mode crosstalk.
Weilun Zhang, Mengyuan Ye, Yunlong Li, Li Liu, Xiangyu Guo, Yu Yu   +5 more
doaj   +1 more source

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Utilizing a clinically relevant course of treatment, our study reveals that glucocorticoids protect against the late NLRP3 inflammasome activation regulating the IL‐1β secretion, the processing of GSDM‐D and pyroptosis following signal 2 stimulation. These potent anti‐inflammatory effects are mediated by the activation of GR signaling and the expansion
David Diaz‐Jimenez, Robert H. Oakley, Jackson A. Hoffman, Carl D. Bortner, Fred Lih, Jianying Li, Jason G. Williams, Erica Scappini, Kevin E. Gerrish, Stavros Garantziotis, Trevor K. Archer, John A. Cidlowski   +11 more
wiley   +1 more source

A Silicon-Based On-Chip 64-Channel Hybrid Wavelength- and Mode-Division (de)Multiplexer

Photonics, 2023
An on-chip 64-channel hybrid (de)multiplexer for wavelength-division multiplexing (WDM) and mode-division multiplexing (MDM) is designed and demonstrated on a 220 nm SOI platform for the demands of large capacity optical interconnections.
Yuxiang Yin, Hang Yu, Donghe Tu, Xingrui Huang, Zhiguo Yu, Huan Guan, Zhiyong Li   +6 more
doaj   +1 more source

Inverse‐Designed on‐Chip Terahertz Three‐Channel Mode and Wavelength Division Demultiplexer

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
An ultracompact terahertz demultiplexer is developed using a hybrid inverse design that combines genetic algorithms with topology optimization. The device enables simultaneous mode‐ and wavelength‐division multiplexing within a footprint smaller than two wavelengths.
Faqian Chong, Yulun Wu, Bingtao Gao, Shilong Li, Hongsheng Chen, Song Han   +5 more
wiley   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence‐Associated Secretory Phenotype in HIV Infection

Aging Cell, Volume 25, Issue 1, January 2026.
The senescence‐associated secretory phenotype (SASP) is one of the main factors contributing to immunosenescence in chronic HIV infection. Extracellular vesicles (EVs) present in the plasma of chronically infected people living with HIV (PLWH) represent an important mechanism for inducing SASP, particularly IL‐6 expression in peripheral cells.
Ricardo Cardoso Castro, Humberto Doriguetto Gravina, Fabrícia Heloísa Cavicchioli Sugiyama, Yann Lamarre, Caroline Fontanari, Bonita Powell, Olesia Gololobova, Zhaohao Liao, Fausto Almeida, Simone Kashima, Kenneth Witwer, Fabiani Gai Frantz   +11 more
wiley   +1 more source

Chip-to-chip optical multimode communication with universal mode processors

PhotoniX, 2023
The increasing amount of data exchange requires higher-capacity optical communication links. Mode division multiplexing (MDM) is considered as a promising technology to support the higher data throughput.
Bo Wu, Wenkai Zhang, Hailong Zhou, Jianji Dong, Dongmei Huang, P. K. A. Wai, Xinliang Zhang   +6 more
doaj   +1 more source

Supermode Characteristics of Nested Multiple Hollow-Core Anti-Resonant Fibers

Photonics, 2022
Mode-division multiplexing (MDM) can achieve ultra-high data capacity in optical fiber communication. Several impressive works on multicore fiber (MCF), multi-mode fiber, and few-mode multicore fiber have made significant achievements in MDM.
Zequan Li, Jiantao Liu, Changming Xia, Zhiyun Hou, Guiyao Zhou   +4 more
doaj   +1 more source

SARS‐CoV‐2‐Induced Macrophage Polarization Reverses HIV‐1 Latency in J‐Lat Cells Through TNFα Signaling

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Introduction Coronavirus disease 2019 (COVID‐19) may have both short‐ and long‐term impacts on the progression of human immunodeficiency virus (HIV)‐1 after acute SARS‐CoV‐2 infection in people living with HIV (PLWH), even those on combined antiretroviral therapy (cART).
Patricio Jarmoluk, Franco Agustín Sviercz, Cintia Cevallos, Rosa Nicole Freiberger, Cynthia Alicia López, M. Victoria Delpino, Jorge Quarleri, Poorani Gurumallesh   +7 more
wiley   +1 more source