Results 51 to 60 of about 431 (135)

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, Volume 13, Issue 18, 27 March 2026.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Mode Division Multiplexing (MDM) Weight Bank Design for Use in Photonic Neural Networks

, 2018
Neural networks provide a powerful tool for applications from classification and regression to general purpose alternative computing. Photonics have the potential to provide enormous speed benefits over electronic and software networks, allowing such networks to be used in real-time applications at radio frequencies. Mode division multiplexing (MDM) is
openaire   +2 more sources

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Utilizing a clinically relevant course of treatment, our study reveals that glucocorticoids protect against the late NLRP3 inflammasome activation regulating the IL‐1β secretion, the processing of GSDM‐D and pyroptosis following signal 2 stimulation. These potent anti‐inflammatory effects are mediated by the activation of GR signaling and the expansion
David Diaz‐Jimenez, Robert H. Oakley, Jackson A. Hoffman, Carl D. Bortner, Fred Lih, Jianying Li, Jason G. Williams, Erica Scappini, Kevin E. Gerrish, Stavros Garantziotis, Trevor K. Archer, John A. Cidlowski   +11 more
wiley   +1 more source

Inverse‐Designed on‐Chip Terahertz Three‐Channel Mode and Wavelength Division Demultiplexer

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
An ultracompact terahertz demultiplexer is developed using a hybrid inverse design that combines genetic algorithms with topology optimization. The device enables simultaneous mode‐ and wavelength‐division multiplexing within a footprint smaller than two wavelengths.
Faqian Chong, Yulun Wu, Bingtao Gao, Shilong Li, Hongsheng Chen, Song Han   +5 more
wiley   +1 more source

Ant-colony optimization-based multi-input multi-output (ACO-MIMO) equalization for low-complexity mode-division multiplexing (MDM) processing

Optics Express
In mode-division multiplexing (MDM) systems, the computational complexity of the multi-input multi-output (MIMO) equalization module is a critical obstacle to practical development. The step size μ and the number of taps K are key parameters in the equalization algorithm, influencing the performance of finite impulse response (FIR) equalizers ...
Tianfeng Zhao, Feng Wen, Bianxia Feng, Feng Tian, Mingming Tan, Baojian Wu, Bo Xu, Kun Qiu   +7 more
openaire   +2 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

A Fast and Effective MIMO Algorithm Using CLR-RNN for Hybrid MDM and WDM Optical Communication System

IEEE Photonics Journal
There is an increasing demand for data with the development of the world, and various fiber optic multiplexing techniques have become an important research direction to improve transmission capacity.
Danni Zhang, Zhongwei Tan, Xinyuan Ma, Shun Lu, Wenhua Ren, Fengping Yan   +5 more
doaj   +1 more source

Add/Drop Mode-Division Multiplexer Based on a Mach–Zehnder Interferometer and Periodic Waveguides

IEEE Photonics Journal, 2015
Mode-division multiplexing (MDM) is currently under study due to its potential to further increase data rates in optical communication circuits. In this paper, we propose an add/drop MDM for the first- and second-order modes that cover the whole C-Band ...
D. Perez-Galacho, D. Marris-Morini, A. Ortega-Monux, J. G. Wanguemert-Perez, L. Vivien   +4 more
doaj   +1 more source

Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence‐Associated Secretory Phenotype in HIV Infection

Aging Cell, Volume 25, Issue 1, January 2026.
The senescence‐associated secretory phenotype (SASP) is one of the main factors contributing to immunosenescence in chronic HIV infection. Extracellular vesicles (EVs) present in the plasma of chronically infected people living with HIV (PLWH) represent an important mechanism for inducing SASP, particularly IL‐6 expression in peripheral cells.
Ricardo Cardoso Castro, Humberto Doriguetto Gravina, Fabrícia Heloísa Cavicchioli Sugiyama, Yann Lamarre, Caroline Fontanari, Bonita Powell, Olesia Gololobova, Zhaohao Liao, Fausto Almeida, Simone Kashima, Kenneth Witwer, Fabiani Gai Frantz   +11 more
wiley   +1 more source

SARS‐CoV‐2‐Induced Macrophage Polarization Reverses HIV‐1 Latency in J‐Lat Cells Through TNFα Signaling

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Introduction Coronavirus disease 2019 (COVID‐19) may have both short‐ and long‐term impacts on the progression of human immunodeficiency virus (HIV)‐1 after acute SARS‐CoV‐2 infection in people living with HIV (PLWH), even those on combined antiretroviral therapy (cART).
Patricio Jarmoluk, Franco Agustín Sviercz, Cintia Cevallos, Rosa Nicole Freiberger, Cynthia Alicia López, M. Victoria Delpino, Jorge Quarleri, Poorani Gurumallesh   +7 more
wiley   +1 more source