Results 111 to 120 of about 8,785,612 (244)

Investigation of mixed mode-I/II fracture problems - Part 2: evaluation and development of mixed mode-I/II fracture criteria

Fracture and Structural Integrity, 2015
In this study, experimental and numerical results of compact tension shear (CTS) specimen and a new specimen type under in-plane mixed mode (Mode-I/II) loading conditions are compared with existing inplane mixed mode fracture criteria to investigate and ...
A. O. Ayhan, O. Demir
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Low frequency room excitation using Distributed Mode Loudspeakers [PDF]

, 2002
Conventional pistonic loudspeakers excite the modes of an enclosed sound field in such a way as to introduce modal artefacts which may be problematic for listeners to high-quality reproduced sound [1].
Fazenda, Bruno, Avis, M.R., Davies, W.J.
core   +1 more source

Comparative analysis of delamination resistance in CFRP laminates interleaved by thermoplastic nanoparticle: Evaluating toughening mechanisms in modes I and II

Composites Part C: Open Access
The study considers the delamination resistance of carbon/epoxy laminates modified with Thermoplastic Nanoparticles of Polysulfone (TNPs). A new electrospinning nanofiber technique was utilized to convert polysulfone polymer into nanoparticles and ...
Reza Mohammadi, R Akrami, Maher Assaad, Ahmed Imran, Mohammad Fotouhi   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Mode und Gender

Mode ist gestaltete Identität und markiert seit jeher Geschlechterdifferenzen. In den Beiträgen aus Wissenschaft und Gestaltung wird erkundet, wie Genderdebatten von der Mode profitieren und wie Modegeschichte durch einen kritischen Genderblick an Profil

core   +1 more source

AE4 - Constantius II - Nicomedia

, 2019
By weight, this object is identified AE4. RIC only attests to various AE3 objects of this type. If mint mark is read correctly as SMNA, then this coin was minted in Nicomedia (cf.

core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Experimental Comparison of Three Liquid Supply System on Plate Freezer

Zhileng xuebao, 2015
This paper proposes a type of ejector throttling refrigeration system (Mode III), and compares it with traditional thermal expansion valve (Mode I) and liquid pump for liquid (Mode II) through experiments.
Cao Xiaocheng, Wan Jinqing, Song Liyao, Li Jianguo, Wang Guoqiang   +4 more
doaj