Results 101 to 110 of about 8,785,612 (244)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
3D Characterization of Mixed-Mode Fracture Toughness of Materials Using a New Loading Device
Latin American Journal of Solids and StructuresIn this paper, a new loading device was employed to conduct a mixed-mode fracture test. Therefore, disadvantages detected in the previous mixed-mode fracture toughness test methods can be avoided.
Abuzar Es'haghi Oskui +2 more
doaj +1 more source
Displacement Rate Effects on the Mode II Shear Delamination Behavior of Carbon Fiber/Epoxy Composites. [PDF]
Polymers (Basel), 2021 Low KO +6 more
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Elaiussa Sebaste II- Un porto fra Oriente e Occidente
, 2003 (a cura di E.Equini Schneider)
II, EQUINI, Eugenia
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Parution: L'Art de la mode, Catherine Örmen
, 2015 Éditions Citadelles&Mazenod, Une approche historique et esthétique du XVIIIe siècles à nos jours avec 600 illustrations (costume, textile, illustrations et photographies de mode) Catherine Örmen viendra présenter son ouvrage le 22 janvier au #SemMode!
Sophie Kurkdjian
core
Mode II Fatigue Crack Propagation
, 1971 Fatigue crack propagation rates were obtained for 2024-T3 bare aluminum plates subjected to in-plane, mode I, extensional loads and transverse, mode II, bending loads.
J. J. Kibler, R. Roberts
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source