Results 81 to 90 of about 8,785,612 (244)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Bryon II

open access: yes, 1994
Chef John Sarich of Chateau St ...
Bryon II
core  

Mixed-mode oscillations with multiple time scales [PDF]

open access: yes, 2010
Mixed-mode oscillations (MMOs) are trajectories of a dynamical system in which there is an alternation between oscillations of distinct large and small amplitudes.
Desroches, MF   +5 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A II. kerület lakosságához!

open access: yes, 2020
1956. nov. 13.II. ker Nemzeti Bizottmány, II.

core  

Mode II fracture of an elastic-plastic sandwich layer [PDF]

open access: yes, 2019
The shear strength of a pre-cracked sandwich layer is predicted, assuming that the layer is linear elastic or elastic-plastic, with yielding characterized either by the J2 plasticity theory or by a strip-yield model.
Cuesta, Ii   +4 more
core   +2 more sources

The Effects of Shear on Mode II Delamination

open access: yesFracture and Structural Integrity, 2018
The paper focuses on the effects of shear deformation and shear forces on the mode II contribution to the energy release rate in delaminated beams. A critical review of the relevant literature is presented, starting from the end-notched flexure test as ...
Paolo Sebastiano Valvo
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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