Results 61 to 70 of about 808,905 (255)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mode I and Mode II Fracture Toughness of Fe-based Amorphous Materials: Theoretical and Empirical Investigations [PDF]

open access: yesJournal of Applied and Computational Mechanics
This study investigates a diagonally loaded square plate specimen's fracture toughness. The specimen has central pre-crakes under loading modes I and II. Iron-based amorphous material with high strain-hardness (200 to 500 MPa) and malleability (10% to 50%
Hamid Al-Abboodi, Mortadha Razzaq
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dynamic properties of mode I and mode II fractures of shale under impact loading

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Controllable shock wave fracturing is an innovative engineering technique used for shale reservoir fracturing and reformation. Understanding the anisotropic fracture mechanism of shale under impact loading is vital for optimizing shock wave fracturing ...
Zelin Yan   +3 more
doaj   +1 more source

Temperature Dependence of Mode II Fracture Toughness

open access: yesJSME international journal. Ser. 1, Solid mechanics, strength of materials, 1988
The ductile-brittle transition behavior of a cracked steel specimen under mode II loading has been studied experimentally. Mode II tests were carried out in the low temperature region on center-cracked thin sheet specimens of two kinds of steels (HT50 and S20C). Mode I tests were also carried out.
TAKAMATSU, Tohru, ICHIKAWA, Masahiro
openaire   +3 more sources

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