Results 51 to 60 of about 8,785,612 (244)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Characterizing Fatigue Delamination Growth in Multidirectional CFRP Laminates

Engineering Proceedings
Despite the popularity of multidirectional laminates in many fatigue-prone design applications, there is still little understanding of how the adjacent plies’ fibre orientation affects interfacial crack (delamination) fatigue propagation.
Davide Biagini, Francisco Monticeli, Yasmine Mosleh, John-Alan Pascoe   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Development of a Finite Element Methodology for Modelling Mixed-Mode Delamination Growth [PDF]

, 2007
A critical failure mechanism for composite skin-stiffened structures in compression is separation of the skin and stiffener, which can be considered analogous to interlaminar cracking.
Degenhardt, Richard, Bayandor, J., Thomson, R.S., Orifici, Adrian, Büsing, S.   +4 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The influence of hydrostatic pressure on the interlaminar fracture toughness of carbon/epoxy composites [PDF]

, 2006
The use of composites for deep sea applications requires a thorough understanding of the behaviour of these materials. While several studies have examined the influence of pressure on in-plane properties few data are available for the interlaminar ...
Peleau, M., Davies, P., Cartié, Denis D. R., Partridge, Ivana K.   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Finite element analysis of the ECT test on mode III interlaminar fracture of carbon-epoxy composite laminates [PDF]

, 2006
In this work a parametric study of the Edge Crack Torsion (ECT) specimen was performed in order to maximize the mode III component (GIII) of the strain energy release rate for carbon-epoxy laminates.
Morais, A. B. de, Moura, M. F. S. F. de, Morais, J. J. L., Silva, M. A. L.   +3 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source