Results 91 to 100 of about 810,769 (296)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Complete CKM quark mixing via dimensional deconstruction

open access: yes, 2004
It is shown that the deconstruction of $[SU(2)\times U(1)]^N$ into $[SU(2)\times U(1)]$ is capable of providing all necessary ingredients to completely impliment the complex CKM mixing of quark flavors.
A. Soddu   +28 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

All-optical mode conversion via spatially multimode four-wave mixing

open access: yesNew Journal of Physics, 2016
We experimentally demonstrate the conversion of a Gaussian beam to an approximate Bessel–Gauss mode by making use of a non-collinear four-wave mixing (4WM) process in hot atomic vapor.
Onur Danaci   +2 more
doaj   +1 more source

Uniform Phase Empirical Mode Decomposition: An Optimal Hybridization of Masking Signal and Ensemble Approaches

open access: yesIEEE Access, 2018
The empirical mode decomposition (EMD) is an established method for the time-frequency analysis of nonlinear and nonstationary signals. However, one major drawback of the EMD is the mode mixing effect.
Yung-Hung Wang, Kun Hu, Men-Tzung Lo
doaj   +1 more source

Displacement-enhanced continuous-variable entanglement concentration

open access: yes, 2012
We study entanglement concentration of continuous variable Gaussian states by local photon subtractions enhanced by coherent displacements. Instead of the previously considered symmetric two-mode squeezed vacuum states, we investigate the protocol for ...
Fiurášek, Jaromír   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Study on influence factors of mixing uniformity for dredged spoil utilized as a resource by PFM with static mixer [PDF]

open access: yesE3S Web of Conferences
The static mixer is a non-moving structure used for mixing fluid medium in the pipeline, and structural parameters are important factors affecting the mixing effect.
Hu Junlong   +4 more
doaj   +1 more source

Multiple-scales analysis of cosmological perturbations in brane-worlds

open access: yes, 2004
We present a new approximation method for solving the equations of motion for cosmological tensor perturbations in a Randall-Sundrum brane-world model of the type with one brane in a five-dimensional anti-de Sitter spacetime.
Battye, Richard A., Mennim, Andrew
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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