Results 91 to 100 of about 198,137 (312)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Uniform Phase Empirical Mode Decomposition: An Optimal Hybridization of Masking Signal and Ensemble Approaches

open access: yesIEEE Access, 2018
The empirical mode decomposition (EMD) is an established method for the time-frequency analysis of nonlinear and nonstationary signals. However, one major drawback of the EMD is the mode mixing effect.
Yung-Hung Wang, Kun Hu, Men-Tzung Lo
doaj   +1 more source

Self-Mixing Diode Laser Interferometry

open access: yes, 2010
Self-mixing interferometry in a laser diode is a very powerful tool in measurement science. The Self-mixing interferometer is a very robust and low cost interferometer with extreme simplicity in alignment and setup.
Shrestha, Pawan Kumar
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

All-optical mode conversion via spatially multimode four-wave mixing

open access: yesNew Journal of Physics, 2016
We experimentally demonstrate the conversion of a Gaussian beam to an approximate Bessel–Gauss mode by making use of a non-collinear four-wave mixing (4WM) process in hot atomic vapor.
Onur Danaci   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Study on influence factors of mixing uniformity for dredged spoil utilized as a resource by PFM with static mixer [PDF]

open access: yesE3S Web of Conferences
The static mixer is a non-moving structure used for mixing fluid medium in the pipeline, and structural parameters are important factors affecting the mixing effect.
Hu Junlong   +4 more
doaj   +1 more source

Dem simulation of continuous pharmaceutical powders mixing effect of non-constant feeding on mixing quality

open access: yes, 2022
In this work, the effect of changing feeding mode(using a “pulsed†one), of active pharmaceutical ingredient (API) on the mixing efficiency were investigated using Discrete Element Method (DEM) simulations.
Pellegrini, Marco
core  

Thermometry based on Whispering Gallery Mode resonators [PDF]

open access: yes, 2012
Whispering gallery (WG) mode resonators were studied since 1980s for precision clock oscillators and for cavity quantum electrodynamics studies. They are a kind of stable, high Q, microwave resonators where a symmetric dielectric medium, such as a ...
Yu, Lili
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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