Results 71 to 80 of about 198,137 (312)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The structure and stability of mode-2 internal solitary-like waves is investigated experimentally. A rank-ordered train of mode-2 internal solitary waves is generated using a lock release configuration.
P. A. Davies +11 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
In order to develop a new mixing procedure, we conduct DNS (direct numerical simulation) of vector controlled free jets. The inflow velocity of jet is periodically oscillated perpendicular to the jet axis.
Koichi TSUJIMOTO +3 more
doaj +1 more source
THE ROLE OF MODE MIXING IN THE ABSORPTION OFp-MODES [PDF]
Observations show that a p-mode may lose up to 70% of its energy flux when it interacts with a sunspot. Part of the absorbed energy is assumed to be converted into other types of waves, while part of it is re-emitted into modes with different radial orders n.
Gordovskyy, M., Jain, R., Hindman, B.W.
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Variational Mode Decomposition (VMD) serves as an effective method for simultaneously decomposing signals into a series of narrowband components. However, its theoretical foundation, the classical Wiener filter, exhibits limited adaptability when applied
Nuo Li, Hang Wang
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Optimizing Approach for Sifting Process to Solve a Common Type of Empirical Mode Decomposition Mode Mixing [PDF]
Empirical mode decomposition (EMD), a new data-driven of time-series decomposition, has the advantage of supposing that a time series is non-linear or non-stationary, as is implicitly achieved in Fourier decomposition.
Karema Al-Subari +3 more
core +1 more source

