Results 51 to 60 of about 168,707,534 (305)

Behavioral fingerprints predict insecticide and anthelmintic mode of action

open access: yesMolecular Systems Biology, 2021
Novel invertebrate‐killing compounds are required in agriculture and medicine to overcome resistance to existing treatments. Because insecticides and anthelmintics are discovered in phenotypic screens, a crucial step in the discovery process is ...
Adam McDermott‐Rouse   +6 more
doaj   +1 more source

Mode of action of azthreonam [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1982
Azthreonam (SQ 26,776) is a member of a new class of monocyclic beta-lactam antibiotics. In Escherichia coli, azthreonam caused filamentation at its lowest effective concentration (0.2 microgram/ml), a morphological effect identical to that observed with cephalothin.
N H, Georgopapadakou   +2 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Novedades CAFRA: Boletin lnformativo de la Asociacion Caribena para la investigacion y accion feministas action femlnistas.

open access: yes, 1990
This collection includes reports, ephemera, images, publications and working papers, which form part of the Caribbean Association of Feminist Research Action (CAFRA ...
Caribbean Association for Feminist Research & Action (CAFRA)
core   +1 more source

Modifications on Labels and Leaflets of Herbicides for Preventing and Managing Resistance [PDF]

open access: yesPlanta Daninha
: The challenge of managing herbicide-resistant weeds is an agricultural reality in Brazil that shall not be neglected. In this sense, Ministério da Agricultura, Pecuária e Abastecimento (MAPA) published Act No.
S.J.P. CARVALHO   +4 more
doaj   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Antibacterial Effect and Mode of Action of Flavonoids From Licorice Against Methicillin-Resistant Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2019
Staphylococcus aureus is a bacterial pathogen that causes food poisoning, various infections, and sepsis. Effective strategies and new drugs are needed to control S.
Shuai-Cheng Wu   +10 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Antibacterial and antibiofilm activity of essential oil of Achillea biebersteinii and its mode of action [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2020
Context: Microbial biofilms and antibiotic-resistant bacterial strains pose a challenge in clinical world as they fail to respond to conventional treatments. This failure of antibiotic treatment led researchers to look for alternatives.
Jehad M. Al-Shuneigat   +3 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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