Results 191 to 200 of about 1,998,737 (342)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Understanding SERS Spectral Shape Variability through Substrate Optics, Molecular Orientation, and Unsupervised Clustering. [PDF]

J Phys Chem C Nanomater Interfaces
Kumar A, Ma F, Chen X, Zhao Y.
europepmc   +1 more source

Study of Apollo water impact. Volume 9 - Mode shapes and natural frequencies analysis Final report

, 1967
Andrea Cappelli
openalex   +1 more source

The fabrication of a thin, circular polymer film based phase shaper for generating doughnut modes

, 2006
Jun‐ichi Hotta, Hiroshi Uji‐i, Johan Hofkens   +2 more
openalex   +1 more source

Introduction: Society, regulation and governance: new modes of shaping social change? [PDF]

, 2017
Regine Paul, Marc Mölders
openalex   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Piezoelectric stepped-plate resonators vibrating at lateral modes for direct viscosity determination in liquids. [PDF]

Microsyst Nanoeng
Huang L, Lu D, Han X, Wu H, Li W, Niu G, Wang K, Yang P, Ren W, Zhao L.   +9 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Determination of Fracture Mechanism and Mode II Fracture Toughness of Red Sandstone Subjected to Compressive-Shear Loading. [PDF]

Materials (Basel)
Lei CH, Liu HZ, Xie HQ, Xiao ML, Feng G, Zheng ZQ.   +5 more
europepmc   +1 more source

D-shape optical fiber pH sensor based on Lossy Mode Resonances (LMRs)

, 2015
Pablo Zubiate, Carlos R. Zamarreño, Ignacio Del Villar, Ignacio R. Matı́as, Francisco J. Arregui   +4 more
openalex   +2 more sources