Results 201 to 210 of about 141,115 (295)

Output-Only Modal Identification of Civil Engineering Structures Based on Parametric Complexity Pursuit. [PDF]

Sensors (Basel)
Li J, Gao J, Zhang S, Mircevska V, Cao M.   +4 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mode shape identification based on monophotogrammetry and relative displacements of partial structures under ambient excitation. [PDF]

Sci Rep
Jinlu L, Hu Y, Gou C, Luo J, Li D.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Beyond Genes: Metabolomic Evidence Indicates Potential Species-Level Differentiation in European Wild Rabbits. [PDF]

J Exp Zool A Ecol Integr Physiol
Cortés-García C, Hedemann MS, Mateo-López J, Llobat L, Cambra-López M, Pascual JJ, García-Bocanegra I, Rouco C, Marín-García PJ.   +8 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A robust strategy for FE model updating of composite panels using a combined ANN-SMA surrogate-assisted optimization framework. [PDF]

Sci Rep
Kouhi M, Mojtahedi A, Lotfollahi-Yaghin MA.   +2 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

High- and low-fidelity modal and mechanical analysis of architected strut-based lattice structures with auxetic topologies. [PDF]

Sci Rep
Shingare KB, Bochare S, Schiffer A, Kinloch I, Liao K.   +4 more
europepmc   +1 more source

Estimation of Rotation Mode Shapes by Use of Numerical Analysis. How to Select Mode Shapes to Be Combined.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1996
KURATANI, Fumiyasu, IWATSUBO, Takuzo, OKITA, Kozo   +2 more
openaire   +2 more sources