Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Phase-Resolved Two-Dimensional Infrared Spectroscopy of Solution-Phase Vibrational Polaritons on Gold Antenna Meta-Surfaces. [PDF]
Sufrin S, Cohn B, Chuntonov L.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Engineered fano resonances in a compact Si<sub>3</sub>N<sub>4</sub> photonic crystal nanobeam-microring platform for multi-cladding environments. [PDF]
Mendoza-Castro JH +6 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Understanding SERS Spectral Shape Variability through Substrate Optics, Molecular Orientation, and Unsupervised Clustering. [PDF]
Kumar A, Ma F, Chen X, Zhao Y.
europepmc +1 more source
TiO<sub>2</sub>-coated guided-mode resonance gratings for polarization-selective green light filtering. [PDF]
Aslam K, Mushtaq N, Chai Y, Kang G.
europepmc +1 more source
Evaluating the Influence of Normalisation Procedures on a Negative Selection Algorithm to Enhance Damage Detection. [PDF]
Barontini A +5 more
europepmc +1 more source
Raman and SERS Spectra of Human Myelin Basic Protein in Cerebrospinal Fluid. [PDF]
Bravo-Oro A +10 more
europepmc +1 more source

