Results 141 to 150 of about 1,500,611 (328)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Model-based clustering for flow and mass cytometry data with clinical information. [PDF]

open access: yesBMC Bioinformatics, 2020
Abe K   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

tclust: An R Package for a Trimming Approach to Cluster Analysis

open access: yesJournal of Statistical Software, 2012
Outlying data can heavily influence standard clustering methods. At the same time, clustering principles can be useful when robustifying statistical procedures.
doaj  

Model-based clustering of multi-tissue gene expression data. [PDF]

open access: yesBioinformatics, 2020
Erola P, Björkegren JLM, Michoel T.
europepmc   +1 more source

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