Results 171 to 180 of about 797,470 (304)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Probabilistic Clustering and Shape Modelling of White Matter Fibre Bundles using Regression Mixtures [PDF]

open access: yes
We present a novel approach for probabilistic clustering of white matter fibre pathways using curve-based regression mixture modelling techniques in 3D curve space. The clustering algorithm is based on a principled method for probabilistic modelling of a
Hojjatoleslami, Ali   +3 more
core  

flowEMMi: an automated model-based clustering tool for microbial cytometric data. [PDF]

open access: yesBMC Bioinformatics, 2019
Ludwig J   +4 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

clues: An R Package for Nonparametric Clustering Based on Local Shrinking [PDF]

open access: yes
Determining the optimal number of clusters appears to be a persistent and controversial issue in cluster analysis. Most existing R packages targeting clustering require the user to specify the number of clusters in advance.
Ruben H. Zamar   +4 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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