RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Heparin-Based Biomaterials for Sustained Release of Growth Factors for Bone Tissue Engineering and Regeneration. [PDF]
Nakayama K +4 more
europepmc +1 more source
Model-Based Engineering for the Integration of Manufacturing Systems with Advanced Analytics
David Lechevalier +4 more
openalex +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Dynamic simulation and intelligent control technology for cutting head load of coal mine roadheader. [PDF]
Feng J, Zhang Y, He Y, Tian M.
europepmc +1 more source
Systems Engineering-Based Model Development: Application to Predictive Simulation of a Net-zero Home
Alan Uy
openalex +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
ESC-YOLOv8: An enhanced deep learning framework for semantic understanding of single-line diagram imagery. [PDF]
Bhanbhro H +6 more
europepmc +1 more source
Model‐based systems engineering and safety assessment: A workflow for mechatronic systems design [PDF]
Imane Bouhali +6 more
openalex +1 more source

